caa a22 4500 445812869 CHVBK 20180317145217.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00411-011-0370-0 doi (NATIONALLICENCE)springer-10.1007/s00411-011-0370-0 Assessment of MIRD data for internal dosimetry using the GATE Monte Carlo code [Elektronische Daten] [Ali Parach, Hossein Rajabi, Mohammad Askari] GATE/GEANT is a Monte Carlo code dedicated to nuclear medicine that allows calculation of the dose to organs of voxel phantoms. On the other hand, MIRD is a well-developed system for estimation of the dose to human organs. In this study, results obtained from GATE/GEANT using Snyder phantom are compared to published MIRD data. For this, the mathematical Snyder phantom was discretized and converted to a digital phantom of 100×200×360 voxels. The activity was considered uniformly distributed within kidneys, liver, lungs, pancreas, spleen, and adrenals. The GATE/GEANT Monte Carlo code was used to calculate the dose to the organs of the phantom from mono-energetic photons of 10, 15, 20, 30, 50, 100, 200, 500, and 1000keV. The dose was converted into specific absorbed fraction (SAF) and the results were compared to the corresponding published MIRD data. On average, there was a good correlation (r 2>0.99) between the two series of data. However, the GATE/GEANT data were on average −0.16±6.22% lower than the corresponding MIRD data for self-absorption. Self-absorption in the lungs was considerably higher in the MIRD compared to the GATE/GEANT data, for photon energies of 10-20keV. As for cross-irradiation to other organs, the GATE/GEANT data were on average +1.5±8.1% higher than the MIRD data, for photon energies of 50-1000keV. For photon energies of 10-30keV, the relative difference was +7.5±67%. It turned out that the agreement between the GATE/GEANT and the MIRD data depended upon absolute SAF values and photon energy. For 10-30keV photons, where the absolute SAF values were small, the uncertainty was high and the effect of cross-section prominent, and there was no agreement between the GATE/GEANT results and the MIRD data. However, for photons of 50-1,000keV, the bias was negligible and the agreement was acceptable. Springer-Verlag, 2011 Parach Ali Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran, Iran aut Rajabi Hossein Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran, Iran aut Askari Mohammad Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran, Iran aut Radiation and Environmental Biophysics Springer-Verlag 50/3(2011-08-01), 441-450 0301-634X 50:3<441 2011 50 411 https://doi.org/10.1007/s00411-011-0370-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00411-011-0370-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Parach Ali Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran, Iran aut NATIONALLICENCE 700 1- Rajabi Hossein Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran, Iran aut NATIONALLICENCE 700 1- Askari Mohammad Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran, Iran aut NATIONALLICENCE 773 0- Radiation and Environmental Biophysics Springer-Verlag 50/3(2011-08-01), 441-450 0301-634X 50:3<441 2011 50 411 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer