caa a22 4500 445816635 CHVBK 20180317145230.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s10815-011-9575-z doi (NATIONALLICENCE)springer-10.1007/s10815-011-9575-z Controversies in IVM [Elektronische Daten] [Shauna Reinblatt, Weon-Young Son, Einat Shalom-Paz, Hananel Holzer] Purpose: To explore four areas of controversy: the benefits of gonadotropin priming, benefits and timing of hCG trigger as well as the ideal protocols for endometrial preparation and luteal support. Methods: A literature review was performed to explore the current evidence Results: Current evidence suggests that Gonadotropin priming in combination with hCG prior to collection benefits patients with normal ovaries. In PCOS patients 10,000IU hCG 38h before retrieval increases the total number and rate of oocyte maturation. Gonadotropin priming may also benefit PCOS patients. The ideal timing of hCG trigger appears to be when the leading follicle is 10-12mm. Sparse data exists regarding luteal support protocols. Conclusions: There is still a need for well-designed studies to establish ideal methods for oocyte priming, timing of retrieval, endometrial preparation and luteal support. Further studies must incorporate both clinical and basic science principles of ovarian, follicular and endometrial physiology. Springer Science+Business Media, LLC, 2011 In-vitro maturation nationallicence Priming nationallicence PCOS nationallicence Unstimulated nationallicence Reinblatt Shauna MUHC Reproductive Center, Department of Obstetrics and Gynecology, Royal Victoria Hospital, H3A 1A1, Montreal, Quebec, Canada aut Son Weon-Young MUHC Reproductive Center, Department of Obstetrics and Gynecology, Royal Victoria Hospital, H3A 1A1, Montreal, Quebec, Canada aut Shalom-Paz Einat MUHC Reproductive Center, Department of Obstetrics and Gynecology, Royal Victoria Hospital, H3A 1A1, Montreal, Quebec, Canada aut Holzer Hananel MUHC Reproductive Center, Department of Obstetrics and Gynecology, Royal Victoria Hospital, H3A 1A1, Montreal, Quebec, Canada aut Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/6(2011-06-01), 525-530 1058-0468 28:6<525 2011 28 10815 https://doi.org/10.1007/s10815-011-9575-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10815-011-9575-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Reinblatt Shauna MUHC Reproductive Center, Department of Obstetrics and Gynecology, Royal Victoria Hospital, H3A 1A1, Montreal, Quebec, Canada aut NATIONALLICENCE 700 1- Son Weon-Young MUHC Reproductive Center, Department of Obstetrics and Gynecology, Royal Victoria Hospital, H3A 1A1, Montreal, Quebec, Canada aut NATIONALLICENCE 700 1- Shalom-Paz Einat MUHC Reproductive Center, Department of Obstetrics and Gynecology, Royal Victoria Hospital, H3A 1A1, Montreal, Quebec, Canada aut NATIONALLICENCE 700 1- Holzer Hananel MUHC Reproductive Center, Department of Obstetrics and Gynecology, Royal Victoria Hospital, H3A 1A1, Montreal, Quebec, Canada aut NATIONALLICENCE 773 0- Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/6(2011-06-01), 525-530 1058-0468 28:6<525 2011 28 10815 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer