caa a22 4500 445816651 CHVBK 20180317145230.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s10815-011-9591-z doi (NATIONALLICENCE)springer-10.1007/s10815-011-9591-z IVM is an alternative for patients with PCO after failed conventional IVF attempt [Elektronische Daten] [Bulent Gulekli, Muge Kovali, Fulya Aydiner, Sule Dogan, Seda Dogan] Purpose: To determine if IVM of oocytes from unstimulated cycle is a treatment option for patients who did not deliver after standard IVF-ET. Method: Twenty three women with PCO, thirteen of them with normal cycles and all <35years old, who failed IVF served as their own control. During the control IVF cycle patients were stimulated with 1730.7 ± 639.5IU recombinant FSH, a long Buserelin acetate protocol was used and embryo transfer was performed on day 2 or 3 after ICSI. After failed IVF immature oocytes were aspirated transvaginally from antral follicles during spontaneous menstrual cycle. Embryo transfer was performed 2 or 3days later. Result: 11.4 ± 4.8 mature oocytes and 6.7 ± 3.2 embryos were produced with IVF, which served as the control, compared to 9.7 ± 4.5 mature oocytes and 6.2 ± 3.2 embryos with IVM. There was one clinical pregnancy in the IVF group which did not result in a live birth where as five singleton and one pair of twins with healthy live births and one miscarriage in the IVM group. Conclusion: IVM does not involve ovarian stimulation with possible financial and health consequences. İt may be an useful treatment after unsuccessful IVF. Springer Science+Business Media, LLC, 2011 IVM nationallicence Live birth rate nationallicence Unstimulated cycle nationallicence Unsuccessful IVF attempt nationallicence Gulekli Bulent Department of Obstetrics & Gynecology, School of Medicine, Dokuz Eylul University Hospital, Izmir, Turkey aut Kovali Muge Department of Obstetrics & Gynecology, School of Medicine, Dokuz Eylul University Hospital, Izmir, Turkey aut Aydiner Fulya Department of Obstetrics & Gynecology, School of Medicine, Dokuz Eylul University Hospital, Izmir, Turkey aut Dogan Sule Department of Obstetrics & Gynecology, School of Medicine, Dokuz Eylul University Hospital, Izmir, Turkey aut Dogan Seda Department of Obstetrics & Gynecology, School of Medicine, Dokuz Eylul University Hospital, Izmir, Turkey aut Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/6(2011-06-01), 495-499 1058-0468 28:6<495 2011 28 10815 https://doi.org/10.1007/s10815-011-9591-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10815-011-9591-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gulekli Bulent Department of Obstetrics & Gynecology, School of Medicine, Dokuz Eylul University Hospital, Izmir, Turkey aut NATIONALLICENCE 700 1- Kovali Muge Department of Obstetrics & Gynecology, School of Medicine, Dokuz Eylul University Hospital, Izmir, Turkey aut NATIONALLICENCE 700 1- Aydiner Fulya Department of Obstetrics & Gynecology, School of Medicine, Dokuz Eylul University Hospital, Izmir, Turkey aut NATIONALLICENCE 700 1- Dogan Sule Department of Obstetrics & Gynecology, School of Medicine, Dokuz Eylul University Hospital, Izmir, Turkey aut NATIONALLICENCE 700 1- Dogan Seda Department of Obstetrics & Gynecology, School of Medicine, Dokuz Eylul University Hospital, Izmir, Turkey aut NATIONALLICENCE 773 0- Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/6(2011-06-01), 495-499 1058-0468 28:6<495 2011 28 10815 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer