caa a22 4500 445816732 CHVBK 20180317145230.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s10815-011-9603-z doi (NATIONALLICENCE)springer-10.1007/s10815-011-9603-z Attitudes of Klinefelter men and their relatives towards TESE-ICSI [Elektronische Daten] [Merel Maiburg, Alissia Hoppenbrouwers, Henk van Stel, Jacques Giltay] Purpose: At the start of the implementation of TESE-ICSI for Klinefelter men in the Netherlands, we aimed to evaluate their wish to father children and their attitudes towards this artificial reproduction technique. Methods: Questionnaires were distributed to members of the Dutch Klinefelter Association (n = 365) and to Klinefelter cases known at our Department (n = 58). Questions addressed several aspects: socio-demographic characteristics, ascertainment of diagnosis, children and child wish, and TESE-ICSI. Data were characterized using descriptive statistics. Results: A total of 260 questionnaires (corresponding to 194 cases, 46%) were returned. A possible wish to father children was reported by 90% of Klinefelter men. 70% of Klinefelter men and 74% of their partners would (probably) opt for TESE-ICSI. Conclusion: The majority of Dutch Klinefelter men and their partners desire to have children and have a positive attitude towards TESE-ICSI. Concerns include the risk of congenital malformations/developmental delay of the child and the limited success rate of TESE-ICSI. The Author(s), 2011 Klinefelter syndrome nationallicence Testicular sperm extraction nationallicence Intracytoplasmic sperm injection nationallicence Child wish nationallicence Questionnaire nationallicence Maiburg Merel Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands aut Hoppenbrouwers Alissia Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands aut van Stel Henk Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands aut Giltay Jacques Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands aut Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/9(2011-09-01), 809-814 1058-0468 28:9<809 2011 28 10815 https://doi.org/10.1007/s10815-011-9603-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10815-011-9603-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Maiburg Merel Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands aut NATIONALLICENCE 700 1- Hoppenbrouwers Alissia Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands aut NATIONALLICENCE 700 1- van Stel Henk Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands aut NATIONALLICENCE 700 1- Giltay Jacques Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands aut NATIONALLICENCE 773 0- Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/9(2011-09-01), 809-814 1058-0468 28:9<809 2011 28 10815 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer