caa a22 4500 445816821 CHVBK 20180317145231.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s10815-011-9604-y doi (NATIONALLICENCE)springer-10.1007/s10815-011-9604-y Melatonin improves the oocyte and the embryo in IVF patients with sleep disturbances, but does not improve the sleeping problems [Elektronische Daten] [Ozlem Eryilmaz, Aysun Devran, Esma Sarikaya, Fatma Aksakal, Leyla Mollamahmutoğlu, Nedim Cicek] Purpose: We aimed to analyse the in vitro fertilization-embryo transfer (IVF-ET) outcomes of the patients with sleep disturbances who were administered melatonin. Methods: A total of 60 patients with sleep disturbances were divided into two groups. The study group (group A, n = 30) had underwent the IVF-ET with melatonin administration and the control group (group B, n = 30) without melatonin. Sleeping status after melatonin administration and the IVF outcomes were compared between the two groups. Results: Sleeping status change was not significant (p > 0.05). The mean number of the retrieved oocytes, the mean MII oocyte counts, the G1 embryo ratio were significantly higher in the melatonin administered group (group A) than that the non-administered group (group B); p = 0.0001; p = 0.0001; p < 0.05 respectively. Conclusion: IVF patients with sleep disorders may benefit from melatonin administration in improving the oocyte and the embryo quality, but the sleeping problem itself may not be fixed. Springer Science+Business Media, LLC, 2011 Melatonin nationallicence IVF nationallicence Sleep disorders nationallicence Eryilmaz Ozlem IVF Department, Zekai Tahir Burak Women Education and Research Hospital, Devlet Mah. Subay Loj.Hızırreis Apt. No:19/11 Yenisehir, Ankara, Turkey aut Devran Aysun IVF Department, Zekai Tahir Burak Women Education and Research Hospital, Devlet Mah. Subay Loj.Hızırreis Apt. No:19/11 Yenisehir, Ankara, Turkey aut Sarikaya Esma IVF Department, Zekai Tahir Burak Women Education and Research Hospital, Devlet Mah. Subay Loj.Hızırreis Apt. No:19/11 Yenisehir, Ankara, Turkey aut Aksakal Fatma Department of Public Health, Faculty of Medicine, Gazi University, Ankara, Turkey aut Mollamahmutoğlu Leyla IVF Department, Zekai Tahir Burak Women Education and Research Hospital, Devlet Mah. Subay Loj.Hızırreis Apt. No:19/11 Yenisehir, Ankara, Turkey aut Cicek Nedim IVF Department, Zekai Tahir Burak Women Education and Research Hospital, Devlet Mah. Subay Loj.Hızırreis Apt. No:19/11 Yenisehir, Ankara, Turkey aut Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/9(2011-09-01), 815-820 1058-0468 28:9<815 2011 28 10815 https://doi.org/10.1007/s10815-011-9604-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10815-011-9604-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Eryilmaz Ozlem IVF Department, Zekai Tahir Burak Women Education and Research Hospital, Devlet Mah. Subay Loj.Hızırreis Apt. No:19/11 Yenisehir, Ankara, Turkey aut NATIONALLICENCE 700 1- Devran Aysun IVF Department, Zekai Tahir Burak Women Education and Research Hospital, Devlet Mah. Subay Loj.Hızırreis Apt. No:19/11 Yenisehir, Ankara, Turkey aut NATIONALLICENCE 700 1- Sarikaya Esma IVF Department, Zekai Tahir Burak Women Education and Research Hospital, Devlet Mah. Subay Loj.Hızırreis Apt. No:19/11 Yenisehir, Ankara, Turkey aut NATIONALLICENCE 700 1- Aksakal Fatma Department of Public Health, Faculty of Medicine, Gazi University, Ankara, Turkey aut NATIONALLICENCE 700 1- Mollamahmutoğlu Leyla IVF Department, Zekai Tahir Burak Women Education and Research Hospital, Devlet Mah. Subay Loj.Hızırreis Apt. No:19/11 Yenisehir, Ankara, Turkey aut NATIONALLICENCE 700 1- Cicek Nedim IVF Department, Zekai Tahir Burak Women Education and Research Hospital, Devlet Mah. Subay Loj.Hızırreis Apt. No:19/11 Yenisehir, Ankara, Turkey aut NATIONALLICENCE 773 0- Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/9(2011-09-01), 815-820 1058-0468 28:9<815 2011 28 10815 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer