caa a22 4500 44581683X CHVBK 20180317145231.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s10815-011-9597-6 doi (NATIONALLICENCE)springer-10.1007/s10815-011-9597-6 Natural cycle IVF/IVM may be more desirable for poor responder patients after failure of stimulated cycles [Elektronische Daten] [Jianhua Li, Ye Xu, Guoping Zhou, Junhong Guo, Nan Xin] Objective: To describe pregnancies and live births resulted from natural cycle IVF combined with in-vitro maturation (natural-cycle IVF/IVM) for three poor responder women after failure of stimulated cycles. Methods: For case 1 and 2, the mature oocytes from aspirated follicles were inseminated by intracytoplasmic sperm injection (ICSI) immediately; immature oocytes were matured in vitro, and the embryos from mature and immature oocytes transferred on day3 after oocyte retrieval. For case 3, 3 consecutive natural cycles were performed, in which the matured oocytes from in vivo or in vitro were vitrified in the first and second cycle, and warmed on the retrieval day of the third fresh cycle. Then the embryos resulted from vitrified-warmed and fresh oocytes were transferred. Results: A total of 15 oocytes were obtained from the 7 retrieval cycles for the three cases. The case 1 was successfully pregnant at her first natural cycle, and case 2 was pregnant after two consecutive cycles. The two cases had successfully delivered and case 3 was in her ongoing pregnancy at the time of submission. Conclusion: These results demonstrate that natural-cycle IVF/IVM might be a reasonable and efficient treatment alternative for poor responder patients when stimulated cycle has failed. Springer Science+Business Media, LLC, 2011 Natural cycle nationallicence In vitro fertilization nationallicence In vitro maturation nationallicence Pregnancy nationallicence Poor responder nationallicence Li Jianhua Center of Reproductive Medicine and Genetics, General Hospital of Beijing Army, 100700, Beijing, China aut Xu Ye Center of Reproductive Medicine and Genetics, General Hospital of Beijing Army, 100700, Beijing, China aut Zhou Guoping Center of Reproductive Medicine and Genetics, General Hospital of Beijing Army, 100700, Beijing, China aut Guo Junhong Center of Reproductive Medicine and Genetics, General Hospital of Beijing Army, 100700, Beijing, China aut Xin Nan Center of Reproductive Medicine and Genetics, General Hospital of Beijing Army, 100700, Beijing, China aut Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/9(2011-09-01), 791-795 1058-0468 28:9<791 2011 28 10815 https://doi.org/10.1007/s10815-011-9597-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10815-011-9597-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Li Jianhua Center of Reproductive Medicine and Genetics, General Hospital of Beijing Army, 100700, Beijing, China aut NATIONALLICENCE 700 1- Xu Ye Center of Reproductive Medicine and Genetics, General Hospital of Beijing Army, 100700, Beijing, China aut NATIONALLICENCE 700 1- Zhou Guoping Center of Reproductive Medicine and Genetics, General Hospital of Beijing Army, 100700, Beijing, China aut NATIONALLICENCE 700 1- Guo Junhong Center of Reproductive Medicine and Genetics, General Hospital of Beijing Army, 100700, Beijing, China aut NATIONALLICENCE 700 1- Xin Nan Center of Reproductive Medicine and Genetics, General Hospital of Beijing Army, 100700, Beijing, China aut NATIONALLICENCE 773 0- Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/9(2011-09-01), 791-795 1058-0468 28:9<791 2011 28 10815 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer