caa a22 4500 445817488 CHVBK 20180317145233.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10815-010-9530-4 doi (NATIONALLICENCE)springer-10.1007/s10815-010-9530-4 Use of the natural cycle and vitrification thawed blastocyst transfer results in better in-vitro fertilization outcomes [Elektronische Daten] Cycle regimens of vitrification thawed blastocyst transfer [Eun Chang, Ji Han, You Kim, Sang Lyu, Woo Lee, Tae Yoon] Purpose: To compare the IVF outcomes of vitrification-thawed blastocyst transfer cycles utilizing different endometrial preparation methods. Methods: We retrospectively assessed IVF outcomes in 611 patients (648 cycles) who underwent blastocyst frozen embryo transfer (FET) between January 2007 and December 2009. All embryos had been cryopreserved by a vitrification method following a previous IVF cycle. Patients were prepared for transfer by using either the natural cycle (n = 310/Group 1), the natural cycle with ovulation induction employing human chorionic gonadotropin (n = 134/Group 2), or a hormonally manipulated artificial cycle with estrogen and progesterone supplementation (n = 204/Group 3). Results: Multivariate logistic regression analysis showed a significant difference in clinical pregnancy rate between Groups 3 (30.4%) and 1 (41.9%) (odds ratio [OR], 0.567; 95% confidence interval [CI], 0.379-0.847, P = 0.006) whereas the difference between Groups 2 and 1 was not significant (41.8% vs. 41.9%; OR, 0.683; 95% CI, 0.435-1.073; P = 0.098). Other significant variables affecting clinical pregnancy rate were the number of embryos transferred, the grade of transferred embryos, and maximal endometrial thickness. Conclusion: The results showed that, using vitrification-thawed blastocyst transfer, employment of natural cycles with or without hCG treatment was associated with better outcomes than was the use of hormonally manipulated cycles. Springer Science+Business Media, LLC, 2011 Cycle regimen nationallicence Vitrification nationallicence Embryo transfer nationallicence Blastocyst nationallicence In vitro fertilization nationallicence Chang Eun Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut Han Ji Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut Kim You Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut Lyu Sang Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut Lee Woo Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut Yoon Tae Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/4(2011-04-01), 369-374 1058-0468 28:4<369 2011 28 10815 https://doi.org/10.1007/s10815-010-9530-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10815-010-9530-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chang Eun Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut NATIONALLICENCE 700 1- Han Ji Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut NATIONALLICENCE 700 1- Kim You Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut NATIONALLICENCE 700 1- Lyu Sang Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut NATIONALLICENCE 700 1- Lee Woo Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut NATIONALLICENCE 700 1- Yoon Tae Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, 650-9 Yeoksam, Kangnamgu, 135-081, Seoul, Korea aut NATIONALLICENCE 773 0- Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/4(2011-04-01), 369-374 1058-0468 28:4<369 2011 28 10815 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer