caa a22 4500 445817569 CHVBK 20180317145233.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10815-010-9534-0 doi (NATIONALLICENCE)springer-10.1007/s10815-010-9534-0 Prognostic value of first IVF cycle on success of a subsequent cycle [Elektronische Daten] [Emmanuel Kalu, Meen-Yau Thum, Hossam Abdalla] Objective: To determine whether a live birth or miscarriage in a previous IVF cycle is predictive of success in a subsequent cycle. Design: Retrospective study Setting: Private IVF unit Patients: 1141 couples having a second IVF cycle. Intervention: 3 groups; Group I: women who had a live birth in the first cycle, Group II those who had a miscarriage, Group III, women who had a negative pregnancy test in their first cycle. Outcome measures: Pregnancy (PR), Live birth (LBR) & miscarriage rates in the second cycle. Results: For women < than 40: PR was 46.4% (368/793), miscarriage rate was 29.9% and the LBR was 32.5% (258/793). Women in groups I & II had a statistically higher PR than those in group III 63.3% v 55.2% v 41.9% respectively. LBR was higher 45% v 37.8 v 29.6% respectively. Miscarriage rate was similar. For women 40years and older: The PR was 21.0% (73/348), miscarriage rate was 52.1% (38/73) and the LBR was 10.1% (35/348).There was no significant difference in PR among women in groups I, II & III. The LBR and miscarriage rates were similar in all groups. Conclusion: Young women who had a live birth and those who experienced an early miscarriage after IVF have a greater likelihood of achieving a live birth in a second cycle. Outcome of first IVF cycle however does not predict subsequent IVF success in older women. Springer Science+Business Media, LLC, 2010 IVF/ICS outcome nationallicence Assisted reproduction nationallicence Miscarriage nationallicence Prognosis nationallicence Kalu Emmanuel Queen Mary's Hospital, Kingston Hospital NHS Trust, KT2 7QB, Kingston Upon Thames, Surrey, UK aut Thum Meen-Yau Lister Fertility Clinic, Lister Hospital, Chelsea Bridge Road, SW1W 8RH, London, UK aut Abdalla Hossam Lister Fertility Clinic, Lister Hospital, Chelsea Bridge Road, SW1W 8RH, London, UK aut Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/4(2011-04-01), 379-382 1058-0468 28:4<379 2011 28 10815 https://doi.org/10.1007/s10815-010-9534-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10815-010-9534-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kalu Emmanuel Queen Mary's Hospital, Kingston Hospital NHS Trust, KT2 7QB, Kingston Upon Thames, Surrey, UK aut NATIONALLICENCE 700 1- Thum Meen-Yau Lister Fertility Clinic, Lister Hospital, Chelsea Bridge Road, SW1W 8RH, London, UK aut NATIONALLICENCE 700 1- Abdalla Hossam Lister Fertility Clinic, Lister Hospital, Chelsea Bridge Road, SW1W 8RH, London, UK aut NATIONALLICENCE 773 0- Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/4(2011-04-01), 379-382 1058-0468 28:4<379 2011 28 10815 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer