caa a22 4500 445817771 CHVBK 20180317145234.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s10815-011-9543-7 doi (NATIONALLICENCE)springer-10.1007/s10815-011-9543-7 The effect of intrafollicular IGF 1 and IGFBP 3 on IVF outcome in patients using different gonadotropins: a prospective study [Elektronische Daten] [Gulay Genc, Nafiye Yilmaz, Dilek Uygur, Muammer Dogan, Leyla Mollamahmutoglu] Aim: To investigate follicular fluid IGF 1, IGFBP 3 and their effects on IVF outcome in patients using different gonadotropins. Materials and methods: This prospective study was performed among 92 IVF patients who were categorized according to IVF pregnancy outcome. Two groups were formed as Group1 : pregnant, Group 2: non pregnant. Results: Follicular IGF 1 and IGFBP 3 levels were not different between the two groups. There were negative correlations between follicular IGF 1 and age, gonadotropin dose, embryo numbers in all patients and group 2, but there were no correlations between IGF1 and these parameters in group 1. Although IGFBP 3 levels were not different in patients using rec FSH or HMG, IGF 1 were higher in patients treated by rec FSH compared to patient using HMG. When the groups using rec FSH or HMG were analyzed according to pregnancy rate, there were no differences in IGF 1 levels. Conclusion: Follicular IGF 1, IGFBP 3 do not predict clinical IVF outcome regardless of the different gonadotropin preparations. Springer Science+Business Media, LLC, 2011 IVF nationallicence IGF1 nationallicence IGFBP 3 nationallicence Follicular fluid nationallicence recFSH nationallicence HMG nationallicence Genc Gulay Department of Infertility, Zekai Tahir Burak Women's Health Research and Education Hospital, Guvenlik cad 54/7, Asagi Ayranci, Ankara, Turkey aut Yilmaz Nafiye Department of Infertility, Zekai Tahir Burak Women's Health Research and Education Hospital, Guvenlik cad 54/7, Asagi Ayranci, Ankara, Turkey aut Uygur Dilek Department of Infertility, Zekai Tahir Burak Women's Health Research and Education Hospital, Guvenlik cad 54/7, Asagi Ayranci, Ankara, Turkey aut Dogan Muammer Department of Infertility, Zekai Tahir Burak Women's Health Research and Education Hospital, Guvenlik cad 54/7, Asagi Ayranci, Ankara, Turkey aut Mollamahmutoglu Leyla Department of Infertility, Zekai Tahir Burak Women's Health Research and Education Hospital, Guvenlik cad 54/7, Asagi Ayranci, Ankara, Turkey aut Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/5(2011-05-01), 405-410 1058-0468 28:5<405 2011 28 10815 https://doi.org/10.1007/s10815-011-9543-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10815-011-9543-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Genc Gulay Department of Infertility, Zekai Tahir Burak Women's Health Research and Education Hospital, Guvenlik cad 54/7, Asagi Ayranci, Ankara, Turkey aut NATIONALLICENCE 700 1- Yilmaz Nafiye Department of Infertility, Zekai Tahir Burak Women's Health Research and Education Hospital, Guvenlik cad 54/7, Asagi Ayranci, Ankara, Turkey aut NATIONALLICENCE 700 1- Uygur Dilek Department of Infertility, Zekai Tahir Burak Women's Health Research and Education Hospital, Guvenlik cad 54/7, Asagi Ayranci, Ankara, Turkey aut NATIONALLICENCE 700 1- Dogan Muammer Department of Infertility, Zekai Tahir Burak Women's Health Research and Education Hospital, Guvenlik cad 54/7, Asagi Ayranci, Ankara, Turkey aut NATIONALLICENCE 700 1- Mollamahmutoglu Leyla Department of Infertility, Zekai Tahir Burak Women's Health Research and Education Hospital, Guvenlik cad 54/7, Asagi Ayranci, Ankara, Turkey aut NATIONALLICENCE 773 0- Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/5(2011-05-01), 405-410 1058-0468 28:5<405 2011 28 10815 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer