caa a22 4500 445818018 CHVBK 20180317145235.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s10815-010-9497-1 doi (NATIONALLICENCE)springer-10.1007/s10815-010-9497-1 Long Y chromosome is not a fetal loss risk [Elektronische Daten] [Hongchuan Nie, Guangxiu Lu] Purpose: To assess the long Y chromosome genetic effect on human pregnancy outcomes. Methods: We studied all records of pregnancies by human sperm donors after artificial insemination or in vitro fertilization at the Reproductive and Genetic Hospital of Citic-Xiangya. Fetal losses were compared from two groups of sperm donors: the observation group (with long Y chromosome) and the control group (without long Y chromosome). Results: 2885 pregnancies were achieved with donor sperm by artificial insemination and 1746 by in vitro fertilization. The rates of fetal loss, congenital malformation and donor fecundity in the observation group after both assisted reproductive technique were the same as for the control group. Conclusions: A long Y chromosome may therefore be considered as a normal variant. Springer Science+Business Media, LLC, 2010 Congenital malformation nationallicence Donor fecundity rate nationallicence Fetal loss nationallicence Long Y chromosome nationallicence Sperm donors nationallicence Nie Hongchuan Institute of Reproduction and Stem Cells Engineering, Central South University, 410078, Changsha, China aut Lu Guangxiu Institute of Reproduction and Stem Cells Engineering, Central South University, 410078, Changsha, China aut Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/2(2011-02-01), 151-156 1058-0468 28:2<151 2011 28 10815 https://doi.org/10.1007/s10815-010-9497-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10815-010-9497-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nie Hongchuan Institute of Reproduction and Stem Cells Engineering, Central South University, 410078, Changsha, China aut NATIONALLICENCE 700 1- Lu Guangxiu Institute of Reproduction and Stem Cells Engineering, Central South University, 410078, Changsha, China aut NATIONALLICENCE 773 0- Journal of Assisted Reproduction and Genetics Springer US; http://www.springer-ny.com 28/2(2011-02-01), 151-156 1058-0468 28:2<151 2011 28 10815 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer