caa a22 4500 445821272 CHVBK 20180317145245.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00239-011-9448-1 doi (NATIONALLICENCE)springer-10.1007/s00239-011-9448-1 Co-Variation Among Major Classes of LRR-Encoding Genes in Two Pairs of Plant Species [Elektronische Daten] [Jiao Wang, Shengjun Tan, Li Zhang, Ping Li, Dacheng Tian] NBS-LRR (nucleotide-binding site-leucine-rich repeat), LRR-RLK (LRR-receptor-like kinase), and LRR-only are the three major LRR-encoding genes. Owing to the crucial role played by them in plant resistance, development, and growth, extensive studies have been performed on the NBS-LRR and LRR-RLK genes. However, few studies have focused on these genes collectively; they may co-vary as all of them contain LRR motifs. To investigate their common evolutionary patterns, all major classes of LRR-encoding genes were identified in 12 plant species, and particularly compared in two pairs of close relatives, Arabidopsis thaliana-A. lyrata (At-Al) and Zea mays-Sorghum bicolor. Our results showed that these genes co-vary significantly in terms of their numbers between species and that the genes with certain evolutionary parameters are most likely to have similar functions. The development-related genes have clear orthologous relationships between closely related species, as well as lower nucleotide divergence, and Ka/Ks ratio. In contrast, resistance-related genes have exactly opposite characteristics and favor 11-15 LRRs per gene. This association could be very useful in predicting the function of LRR-encoding genes. The presence of co-variation suggests that LRRs, combined with other domains, can work better in some common functions. In order to cooperate efficiently, there should be balanced gene numbers among the different gene classes. Springer Science+Business Media, LLC, 2011 LRR-encoding gene nationallicence Co-variation nationallicence Resistance-related genes nationallicence Closely related species nationallicence Leucine-rich repeat nationallicence Wang Jiao State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210093, Nanjing, China aut Tan Shengjun State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210093, Nanjing, China aut Zhang Li State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210093, Nanjing, China aut Li Ping Rice Research Institute, Sichuan Agricultural University, 611130, Wenjiang, China aut Tian Dacheng State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210093, Nanjing, China aut Journal of Molecular Evolution Springer-Verlag 72/5-6(2011-06-01), 498-509 0022-2844 72:5-6<498 2011 72 239 https://doi.org/10.1007/s00239-011-9448-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00239-011-9448-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Jiao State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210093, Nanjing, China aut NATIONALLICENCE 700 1- Tan Shengjun State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210093, Nanjing, China aut NATIONALLICENCE 700 1- Zhang Li State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210093, Nanjing, China aut NATIONALLICENCE 700 1- Li Ping Rice Research Institute, Sichuan Agricultural University, 611130, Wenjiang, China aut NATIONALLICENCE 700 1- Tian Dacheng State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210093, Nanjing, China aut NATIONALLICENCE 773 0- Journal of Molecular Evolution Springer-Verlag 72/5-6(2011-06-01), 498-509 0022-2844 72:5-6<498 2011 72 239 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer