caa a22 4500 445821299 CHVBK 20180317145245.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00239-011-9442-7 doi (NATIONALLICENCE)springer-10.1007/s00239-011-9442-7 Evolutionary Dynamics of the mS952 Intron: A Novel Mitochondrial Group II Intron Encoding a LAGLIDADG Homing Endonuclease Gene [Elektronische Daten] [Sahra-Taylor Mullineux, Karla Willows, Georg Hausner] Examination of the mitochondrial small subunit ribosomal RNA (rns) gene of five species of the fungal genus Leptographium revealed that the gene has been invaded at least once at position 952 by a group II intron encoding a LAGLIDADG homing endonuclease gene. Phylogenetic analyses of the intron and homing endonuclease sequences indicated that each element in Leptographium species forms a single clade and is closely related to the group II intron/homing endonuclease gene composite element previously reported at position 952 of the mitochondrial rns gene of Cordyceps species and of Cryphonectria parasitica. The results of an intron survey of the mt rns gene of Leptographium species superimposed onto the phylogenetic analysis of the host organisms suggest that the composite element was transmitted vertically in Leptographium lundbergii. However, its stochastic distribution among strains of L. wingfieldii, L. terebrantis, and L. truncatum suggests that it has been horizontally transmitted by lateral gene transfer among these species, although the random presence of the intron may reflect multiple random loss events. A model is proposed describing the initial invasion of the group II intron in the rns gene of L. lundbergii by a LAGLIDADG homing endonuclease gene and subsequent evolution of this gene to recognize a novel DNA target site, which may now promote the mobility of the intron and homing endonuclease gene as a composite element. Springer Science+Business Media, LLC, 2011 Mitochondrial group II introns nationallicence Homing endonucleases nationallicence rns Gene nationallicence Ascomycetes nationallicence Mullineux Sahra-Taylor Department of Microbiology, University of Manitoba, R3T 2N2, Winnipeg, MB, Canada aut Willows Karla Department of Microbiology, University of Manitoba, R3T 2N2, Winnipeg, MB, Canada aut Hausner Georg Department of Microbiology, University of Manitoba, R3T 2N2, Winnipeg, MB, Canada aut Journal of Molecular Evolution Springer-Verlag 72/5-6(2011-06-01), 433-449 0022-2844 72:5-6<433 2011 72 239 https://doi.org/10.1007/s00239-011-9442-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00239-011-9442-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mullineux Sahra-Taylor Department of Microbiology, University of Manitoba, R3T 2N2, Winnipeg, MB, Canada aut NATIONALLICENCE 700 1- Willows Karla Department of Microbiology, University of Manitoba, R3T 2N2, Winnipeg, MB, Canada aut NATIONALLICENCE 700 1- Hausner Georg Department of Microbiology, University of Manitoba, R3T 2N2, Winnipeg, MB, Canada aut NATIONALLICENCE 773 0- Journal of Molecular Evolution Springer-Verlag 72/5-6(2011-06-01), 433-449 0022-2844 72:5-6<433 2011 72 239 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer