caa a22 4500 445823666 CHVBK 20180317145252.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s00246-010-9797-3 doi (NATIONALLICENCE)springer-10.1007/s00246-010-9797-3 Eisenmenger Ventricular Septal Defect: Classification, Morphology, and Indications for Surgery [Elektronische Daten] [Huiwen Chen, Zhiwei Xu, Shunmin Wang, Jia Shen, Zhifang Zhang, Haifa Hong] This study aimed to examine the definition and indications for surgery, to elucidate the morphologic substrate of aortic regurgitation, and to extrapolate the pathologic mechanisms of subpulmonary stenosis in Eisenmenger ventricular septal defect (EVSD). The study enrolled 160 patients. Preoperative respiratory symptoms and poor growth were present in 41 patients (26%), and 21 patients (13%) required mechanical ventilation. Perimembranous ventricular septal defect (pVSD) had been diagnosed previously for 136 of the patients (85%) at other institutions. Of the 160 patients, 51 (32%) had muscular posteroinferior rims. Aortic regurgitation was experienced by 36 patients (23%), found to be mild in 31 cases (19%) and moderate in 5 cases (3%). None of the patients had severe regurgitation. No aortic valvuloplasty was performed. The significant risk factors for aortic regurgitation were subpulmonary stenosis (p=0.001) and a muscular posteroinferior rim (p=0.000). Subpulmonary stenosis was seen in 57 patients (35%), found to be mild to moderate in 42 cases (26%) and severe in 15 cases (9%). Adequacy of the stenosis band was repaired through the tricuspid valve for 57 of these patients. The definition of EVSD should identify it as a subgroup different from pVSD, and it should be closed as soon as it is identified in developing countries. Aortic regurgitation occurs rarely, and aortic valvoplasty should be performed if it exceeds a moderate level. The subpulmonary stenosis can be repaired through the tricuspid valve. Springer Science+Business Media, LLC, 2010 Aortic regurgitation nationallicence Eisenmenger ventricular septal defect nationallicence Subpulmonary stenosis nationallicence Chen Huiwen Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut Xu Zhiwei Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut Wang Shunmin Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut Shen Jia Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut Zhang Zhifang Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut Hong Haifa Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut Pediatric Cardiology Springer-Verlag 32/1(2011-01-01), 17-23 0172-0643 32:1<17 2011 32 246 https://doi.org/10.1007/s00246-010-9797-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00246-010-9797-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chen Huiwen Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut NATIONALLICENCE 700 1- Xu Zhiwei Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut NATIONALLICENCE 700 1- Wang Shunmin Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut NATIONALLICENCE 700 1- Shen Jia Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut NATIONALLICENCE 700 1- Zhang Zhifang Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut NATIONALLICENCE 700 1- Hong Haifa Department of Heart Center, Shanghai Children Medical Center, Shanghai Jiao Tong University, 1678 Dongfang Road, 200127, Shanghai, China aut NATIONALLICENCE 773 0- Pediatric Cardiology Springer-Verlag 32/1(2011-01-01), 17-23 0172-0643 32:1<17 2011 32 246 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer