caa a22 4500 445824077 CHVBK 20180317145253.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00246-011-9975-y doi (NATIONALLICENCE)springer-10.1007/s00246-011-9975-y Myocardial Perfusion and Exercise Capacity 12Years After Arterial Switch Surgery for D-Transposition of the Great Arteries [Elektronische Daten] [Lauren Sterrett, Marcus Schamberger, Eric Ebenroth, Aslam Siddiqui, Roger Hurwitz] Peak exercise myocardial perfusion was evaluated in patients with D-transposition of the great arteries 12years after the arterial switch operation (SWITCH) to evaluate coronary perfusion. Gas-exchange measurements were used to assess cardiac limiting factors to exercise capacity in SWITCH patients when compared to healthy gender-matched controls (CON). Peak myocardial perfusion was evaluated in 42 patients 12years post-SWITCH, using technetium-99m (Tetrofosmin). SWITCH exercise data was compared to 42 gender-matched controls (CON). One symptomatic and one asymptomatic SWITCH patient had abnormal exercise myocardial perfusion; both patients had variant coronary anatomy preoperatively. SWITCH patients had lower VO2peak (p<0.01), peak heart rates (p=0.01), percentages of age-predicted peak heart rates (p<0.01), and peak oxygen pulses indexed to body surface area (p<0.01) than CON patients. Exercise testing with myocardial perfusion imaging helped to identify the rare SWITCH patient with coronary insufficiencies. This study demonstrates that exercise testing with myocardial perfusion scans can help identify patients at risk for myocardial events. This study also demonstrated that SWITCH patients have a mildly diminished VO2peak when compared to CON patients. Springer Science+Business Media, LLC, 2011 Arterial switch nationallicence Myocardial perfusion nationallicence Exercise nationallicence Sterrett Lauren Department of Pediatric Cardiology, Riley Hospital for Children at Indiana University, 46202-5225, Indianapolis, IN, USA aut Schamberger Marcus Department of Pediatric Cardiology, Riley Hospital for Children at Indiana University, 46202-5225, Indianapolis, IN, USA aut Ebenroth Eric Department of Pediatric Cardiology, Riley Hospital for Children at Indiana University, 46202-5225, Indianapolis, IN, USA aut Siddiqui Aslam Department of Radiology, Riley Hospital for Children at Indiana University Medical School, 46202-5225, Indianapolis, IN, USA aut Hurwitz Roger Department of Pediatric Cardiology, Riley Hospital for Children at Indiana University, 46202-5225, Indianapolis, IN, USA aut Pediatric Cardiology Springer-Verlag 32/6(2011-08-01), 785-791 0172-0643 32:6<785 2011 32 246 https://doi.org/10.1007/s00246-011-9975-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00246-011-9975-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sterrett Lauren Department of Pediatric Cardiology, Riley Hospital for Children at Indiana University, 46202-5225, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Schamberger Marcus Department of Pediatric Cardiology, Riley Hospital for Children at Indiana University, 46202-5225, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Ebenroth Eric Department of Pediatric Cardiology, Riley Hospital for Children at Indiana University, 46202-5225, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Siddiqui Aslam Department of Radiology, Riley Hospital for Children at Indiana University Medical School, 46202-5225, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Hurwitz Roger Department of Pediatric Cardiology, Riley Hospital for Children at Indiana University, 46202-5225, Indianapolis, IN, USA aut NATIONALLICENCE 773 0- Pediatric Cardiology Springer-Verlag 32/6(2011-08-01), 785-791 0172-0643 32:6<785 2011 32 246 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer