caa a22 4500 445824204 CHVBK 20180317145254.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00246-011-0007-8 doi (NATIONALLICENCE)springer-10.1007/s00246-011-0007-8 Short-Term Outcomes of Acute Fulminant Myocarditis in Children [Elektronische Daten] [Jhuma Sankar, Sumaira Khalil, M. Jeeva Sankar, Dinesh Kumar, Nandkishore Dubey] Data on the clinical profile, echocardiographic findings, and outcome of acute fulminant myocarditis (AFM) in children from resource limited countries are limited. To study the clinical profile and short-term outcomes of children aged 2months to 17years with AFM managed with only supportive care. We enrolled all children admitted with AFM in our hospital from January 2009 to October 2010. Although the information on patients admitted from January 2009 to March 2010 were retrieved from the case records, data of children admitted from April 2010 were recorded prospectively. AFM was diagnosed based on clinical and echocardiographic criteria. We collected information regarding clinical course, treatment details, and echocardiography findings using a structured performa. All of the children, including those for whom baseline information was collected from the records, were followed-up prospectively to determine short-term outcomes. A total of 10 children, of whom 6 were male, presented with AFM. Their median age was 7.5 (interquartile range [IQR] 2 to13) years, and the mean left-ventricular ejection fraction (LVEF) was 26% (SD 11.5). Of the 10 children, 9 were discharged, and 1 child died. At discharge, all children showed improvement in the symptoms, but only 4 had improvement in LV function on echocardiography. Factors associated with poor recovery of LV function at discharge were anasarca, low LVEF, and increased serum glutamate pyruvate transaminase levels at admission. One child had died at 2-month follow-up, and another child developed dilated cardiomyopathy at 15months after discharge. Children with AFM had good immediate- and short-term outcomes even without the use of mechanical assist devices. Decreased LVEF at admission was found to be one of the most important determinants of poor immediate outcomes in these children. Springer Science+Business Media, LLC, 2011 Myocarditis nationallicence Heart failure nationallicence Cardiogenic shock nationallicence Echocardiography nationallicence Outcome nationallicence Children nationallicence Sankar Jhuma Department of Pediatrics, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India aut Khalil Sumaira Department of Pediatrics, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India aut Jeeva Sankar M. Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India aut Kumar Dinesh Department of Pediatrics, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India aut Dubey Nandkishore Department of Pediatrics, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India aut Pediatric Cardiology Springer-Verlag 32/7(2011-10-01), 885-890 0172-0643 32:7<885 2011 32 246 https://doi.org/10.1007/s00246-011-0007-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00246-011-0007-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sankar Jhuma Department of Pediatrics, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India aut NATIONALLICENCE 700 1- Khalil Sumaira Department of Pediatrics, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India aut NATIONALLICENCE 700 1- Jeeva Sankar M. Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India aut NATIONALLICENCE 700 1- Kumar Dinesh Department of Pediatrics, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India aut NATIONALLICENCE 700 1- Dubey Nandkishore Department of Pediatrics, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India aut NATIONALLICENCE 773 0- Pediatric Cardiology Springer-Verlag 32/7(2011-10-01), 885-890 0172-0643 32:7<885 2011 32 246 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer