caa a22 4500 445824867 CHVBK 20180317145256.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00246-011-9908-9 doi (NATIONALLICENCE)springer-10.1007/s00246-011-9908-9 Ventricular Repolarization Lability in Children With Kawasaki Disease [Elektronische Daten] [Marina Kuriki, Masayuki Fujino, Ken-ichi Tanaka, Kayo Horio, Hirofumi Kusuki, Misa Hosoi, Yoshihiko Eryu, Tomochika Kato, Toshio Yamazaki, Tadayoshi Hata] Kawasaki disease (KD) is an acute febrile disease of unknown etiology that develops in children and is sometimes accompanied by myocardial dysfunction and systemic vasculitis. However, myocardial repolarization lability has not yet been fully investigated. Thus, the objective of this study was to evaluate myocardial repolarization lability (QT variability index—QTVI) based on the body surface electrocardiograms in the acute and recovery phases. The subjects were 25 children with acute KD who were hospitalized for treatment. An equal number of age-matched healthy children were selected as controls. The RR-intervals and QT-intervals were measured based on a body surface electrocardiogram of 120 consecutive heartbeats to calculate the QTVI. The QTVI values were then compared with the acute and recovery phases. The relationships between blood biochemistry data and QTVI values were also examined. QTVI was significantly decreased from the acute phase to the recovery phase (P<0.05) and then recovered to the same level as that of the control. QTVI in the acute phase showed a significant positive relationship with body temperature and C-reactive protein (P<0.05). QTVI was high in the acute phase and was correlated with an inflammatory reaction and became normalized during the recovery phase. The Author(s), 2011 Kawasaki disease nationallicence Ventricular repolarization instability nationallicence QT interval variability nationallicence Kuriki Marina Graduate School of Health Sciences, Fujita Health University, Toyoake, Japan aut Fujino Masayuki Department of Pediatrics, Fujita Health University, Toyoake, Japan aut Tanaka Ken-ichi Department of Pediatrics, Toyokawa Municipal Hospital, Toyokawa, Japan aut Horio Kayo Graduate School of Health Sciences, Fujita Health University, Toyoake, Japan aut Kusuki Hirofumi Clinical Laboratory, Mie University Hospital, Tsu, Japan aut Hosoi Misa Clinical Laboratory, Fujita Health University Hospital, Toyoake, Japan aut Eryu Yoshihiko Department of Pediatrics, Fujita Health University, Toyoake, Japan aut Kato Tomochika Department of Pediatrics, Toyokawa Municipal Hospital, Toyokawa, Japan aut Yamazaki Toshio Department of Pediatrics, Fujita Health University, Toyoake, Japan aut Hata Tadayoshi Graduate School of Health Sciences, Fujita Health University, Toyoake, Japan aut Pediatric Cardiology Springer-Verlag 32/4(2011-04-01), 487-491 0172-0643 32:4<487 2011 32 246 https://doi.org/10.1007/s00246-011-9908-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00246-011-9908-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kuriki Marina Graduate School of Health Sciences, Fujita Health University, Toyoake, Japan aut NATIONALLICENCE 700 1- Fujino Masayuki Department of Pediatrics, Fujita Health University, Toyoake, Japan aut NATIONALLICENCE 700 1- Tanaka Ken-ichi Department of Pediatrics, Toyokawa Municipal Hospital, Toyokawa, Japan aut NATIONALLICENCE 700 1- Horio Kayo Graduate School of Health Sciences, Fujita Health University, Toyoake, Japan aut NATIONALLICENCE 700 1- Kusuki Hirofumi Clinical Laboratory, Mie University Hospital, Tsu, Japan aut NATIONALLICENCE 700 1- Hosoi Misa Clinical Laboratory, Fujita Health University Hospital, Toyoake, Japan aut NATIONALLICENCE 700 1- Eryu Yoshihiko Department of Pediatrics, Fujita Health University, Toyoake, Japan aut NATIONALLICENCE 700 1- Kato Tomochika Department of Pediatrics, Toyokawa Municipal Hospital, Toyokawa, Japan aut NATIONALLICENCE 700 1- Yamazaki Toshio Department of Pediatrics, Fujita Health University, Toyoake, Japan aut NATIONALLICENCE 700 1- Hata Tadayoshi Graduate School of Health Sciences, Fujita Health University, Toyoake, Japan aut NATIONALLICENCE 773 0- Pediatric Cardiology Springer-Verlag 32/4(2011-04-01), 487-491 0172-0643 32:4<487 2011 32 246 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer