caa a22 4500 445825235 CHVBK 20180317145257.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00246-011-0040-7 doi (NATIONALLICENCE)springer-10.1007/s00246-011-0040-7 Heart Rate Variability and Exercise Capacity of Patients With Repaired Tetralogy of Fallot [Elektronische Daten] [Suchaya Silvilairat, Jatuporn Wongsathikun, Rekwan Sittiwangkul, Yupada Pongprot, Nipon Chattipakorn] Heart rate variability (HRV) has been used as a reliable method to detect cardiac autonomic nervous system activity. Peak oxygen uptake (VO2 peak) has been a predictor of death for adults with repaired tetralogy of Fallot (TOF). This study investigated the correlation between HRV and exercise capacity in 30 patients with TOF after surgery for total correction. The median age of the patients was 14years (range, 9-25years), and the median follow-up period was 11.6months (range, 5.3-20.2months). Low- and high-frequency-domain HRV significantly correlated with VO2 peak (r=0.56, P=0.001 and r=0.44, P=0.02, respectively). After the 1-year follow-up evaluation, VO2 peak and HRV analysis did not differ from those at entry to the study. However, low- and high-frequency-domain HRV still correlated significantly with VO2 peak (r=0.43, P=0.03 and r=0.52, P=0.007, respectively). Left ventricular early diastolic myocardial velocity was most closely correlated with the VO2 peak (r=0.51, P=0.005). Impaired cardiovascular autonomic control and left ventricular diastolic dysfunction may be responsible for exercise intolerance in patients with repaired TOF. Long-term follow-up evaluation with exercise testing and 24-h Holter monitoring are warranted. Springer Science+Business Media, LLC, 2011 Exercise capacity nationallicence Heart rate variability nationallicence Repaired tetralogy of Fallot nationallicence Silvilairat Suchaya Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, 50200, Chiang Mai, Thailand aut Wongsathikun Jatuporn Department of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, 50200, Chiang Mai, Thailand aut Sittiwangkul Rekwan Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, 50200, Chiang Mai, Thailand aut Pongprot Yupada Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, 50200, Chiang Mai, Thailand aut Chattipakorn Nipon Cardiac Electrophysiology Research and Training Center, Chiang Mai University, 50200, Chiang Mai, Thailand aut Pediatric Cardiology Springer-Verlag 32/8(2011-12-01), 1158-1163 0172-0643 32:8<1158 2011 32 246 https://doi.org/10.1007/s00246-011-0040-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00246-011-0040-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Silvilairat Suchaya Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, 50200, Chiang Mai, Thailand aut NATIONALLICENCE 700 1- Wongsathikun Jatuporn Department of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, 50200, Chiang Mai, Thailand aut NATIONALLICENCE 700 1- Sittiwangkul Rekwan Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, 50200, Chiang Mai, Thailand aut NATIONALLICENCE 700 1- Pongprot Yupada Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, 50200, Chiang Mai, Thailand aut NATIONALLICENCE 700 1- Chattipakorn Nipon Cardiac Electrophysiology Research and Training Center, Chiang Mai University, 50200, Chiang Mai, Thailand aut NATIONALLICENCE 773 0- Pediatric Cardiology Springer-Verlag 32/8(2011-12-01), 1158-1163 0172-0643 32:8<1158 2011 32 246 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer