caa a22 4500 445825707 CHVBK 20180317145258.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00246-011-9915-x doi (NATIONALLICENCE)springer-10.1007/s00246-011-9915-x Validation of Cardiac Output Measurement by Ultrasound Dilution Technique With Pulmonary Artery Thermodilution in a Pediatric Animal Model [Elektronische Daten] [Edward Darling, Naveen Thuramalla, Bruce Searles] Novel COstatus system (Transonic Systems, Inc., NY), based on ultrasound dilution (UD), works off in situ arterial and central venous catheters in pediatric patients to measure cardiac output (CO). The purpose of the present study was to validate CO measurement by UD (COUD) with pulmonary artery (PA) thermodilution (COTD) in a prospective animal study. Ten anesthetized pigs (16-45kg) were instrumented with pediatric PA, central venous, and peripheral artery catheters. For COUD measurements, normothermic saline (0.5-1.0ml/kg body weight, up to a maximum of30ml) was injected into the venous limb of an arteriovenous loop that was connected between in situ catheters. For COTD measurements, 5-10ml cold saline was injected into the PA catheter. Sixty-four averaged sets were obtained for comparison. COTD mean was 2.98±1.21l/min (range 1.33-6.29), and COUD mean was 2.68±1.16l/min (range 1.33-5.85). This study yielded a correlation r=0.96, COUD=0.91*(COTD)−0.04l/min; bias was 0.3l/min with limits of agreement as −0.39 to 0.99l/min; and the percentage error was 23.73% between the methods. CO measurements by UD agreed well with thermodilution measurements in the pediatric swine model. Springer Science+Business Media, LLC, 2011 Pediatric nationallicence Cardiac output nationallicence Ultrasound dilution nationallicence Thermodilution nationallicence Animal validation nationallicence Darling Edward Department of Perfusion, SUNY Upstate Medical University, 13210, Syracuse, NY, USA aut Thuramalla Naveen Transonic Systems Inc, Ithaca, NY, USA aut Searles Bruce Department of Perfusion, SUNY Upstate Medical University, 13210, Syracuse, NY, USA aut Pediatric Cardiology Springer-Verlag 32/5(2011-06-01), 585-589 0172-0643 32:5<585 2011 32 246 https://doi.org/10.1007/s00246-011-9915-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00246-011-9915-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Darling Edward Department of Perfusion, SUNY Upstate Medical University, 13210, Syracuse, NY, USA aut NATIONALLICENCE 700 1- Thuramalla Naveen Transonic Systems Inc, Ithaca, NY, USA aut NATIONALLICENCE 700 1- Searles Bruce Department of Perfusion, SUNY Upstate Medical University, 13210, Syracuse, NY, USA aut NATIONALLICENCE 773 0- Pediatric Cardiology Springer-Verlag 32/5(2011-06-01), 585-589 0172-0643 32:5<585 2011 32 246 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer