caa a22 4500 445825898 CHVBK 20180317145259.0 cr unu---uuuuu 170323e20110601xx s 000 0 eng 10.1007/s00246-011-9931-x doi (NATIONALLICENCE)springer-10.1007/s00246-011-9931-x Cross-Sectional Analysis of Cardiovascular Risk Factors in Children With Parental History of Premature Ischemic Heart Disease [Elektronische Daten] [Gal Neuman, Itai Shavit, Doron Aronson, Avraham Lorber, Diana Gaitini, Roy Onn, Naim Shehadeh] This study aimed to evaluate the presence of cardiovascular risk factors in children with a parental history of premature ischemic heart disease (two- or three-vessel disease diagnosed before the age of 55 in men and 65 in women). A prospective cross-sectional study was performed on 55 children. The following parameters were assessed: body mass index (BMI), waist and hip circumference, blood pressure, lipids profile, fasting glucose (FG), C-reactive protein (CRP), and carotid intimal-medial thickness (CIMT). Twenty-eight children had hypercholesterolemia, and 11 had other forms of dyslipidemia. Sixteen children had a high BMI; 17 had increased CRP levels; 2 were hypertensive; and 2 had impaired FG. CIMT levels were not correlated with age (Pearson r=−0.486; p=0.78) and height (Pearson r=−6.31; p=0.84), but they were correlated with cholesterol levels (Spearman r=0.375; p<0.005). Most patients (83%) had ≥2 risk factors; half of them had ≥3 risk factors. We concluded that these at-risk children should be carefully screened for all known risk factors. Springer Science+Business Media, LLC, 2011 Ischemic heart disease nationallicence Cardiovascular disease nationallicence Risk factors nationallicence Children nationallicence Parental nationallicence Neuman Gal Department of Pediatrics, Meyer Children's Hospital, Rambam Health Care Campus, Haifa, Israel aut Shavit Itai Department of Pediatrics, Meyer Children's Hospital, Rambam Health Care Campus, Haifa, Israel aut Aronson Doron Technion Faculty of Medicine, Haifa, Israel aut Lorber Avraham Technion Faculty of Medicine, Haifa, Israel aut Gaitini Diana Technion Faculty of Medicine, Haifa, Israel aut Onn Roy Department of Pediatrics, Meyer Children's Hospital, Rambam Health Care Campus, Haifa, Israel aut Shehadeh Naim Department of Pediatrics, Meyer Children's Hospital, Rambam Health Care Campus, Haifa, Israel aut Pediatric Cardiology Springer-Verlag 32/5(2011-06-01), 628-633 0172-0643 32:5<628 2011 32 246 https://doi.org/10.1007/s00246-011-9931-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00246-011-9931-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Neuman Gal Department of Pediatrics, Meyer Children's Hospital, Rambam Health Care Campus, Haifa, Israel aut NATIONALLICENCE 700 1- Shavit Itai Department of Pediatrics, Meyer Children's Hospital, Rambam Health Care Campus, Haifa, Israel aut NATIONALLICENCE 700 1- Aronson Doron Technion Faculty of Medicine, Haifa, Israel aut NATIONALLICENCE 700 1- Lorber Avraham Technion Faculty of Medicine, Haifa, Israel aut NATIONALLICENCE 700 1- Gaitini Diana Technion Faculty of Medicine, Haifa, Israel aut NATIONALLICENCE 700 1- Onn Roy Department of Pediatrics, Meyer Children's Hospital, Rambam Health Care Campus, Haifa, Israel aut NATIONALLICENCE 700 1- Shehadeh Naim Department of Pediatrics, Meyer Children's Hospital, Rambam Health Care Campus, Haifa, Israel aut NATIONALLICENCE 773 0- Pediatric Cardiology Springer-Verlag 32/5(2011-06-01), 628-633 0172-0643 32:5<628 2011 32 246 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer