caa a22 4500 445826118 CHVBK 20180317145259.0 cr unu---uuuuu 170323e20110201xx s 000 0 eng 10.1007/s00246-010-9838-y doi (NATIONALLICENCE)springer-10.1007/s00246-010-9838-y The 30-Year Outcome for Patients After Myocardial Infarction Due to Coronary Artery Lesions Caused By Kawasaki Disease [Elektronische Daten] [Etsuko Tsuda, Takuya Hirata, Osamu Matsuo, Tadaaki Abe, Hisashi Sugiyama, Osamu Yamada] This study determined the long-term outcome for patients after myocardial infarction (MI) due to Kawasaki disease (KD). Retrospective analysis was performed for 60 patients who had experienced MI between 1976 and 2007. Their ages at the initial MI ranged from 3months to 33years (median, 2years). The maximum follow-up period after the initial MI was 33years (median, 16years). Coronary angiography, left ventriculography, and radioisotope myocardial perfusion imaging (MPI) had been performed for 56 patients more than 2months after MI when all were in stable condition. The survival rate and ventricular tachycardia (VT)-free survival rate were calculated after the initial MI by the Kaplan-Meier method. Both sustained and nonsustained VT were included. Furthermore, the Cox proportional hazards model was used to analyze which factors influenced the post-MI outcome and which influenced the appearance of VT. The 30-year survival rate was 62.7% (95% confidence interval [CI], 44.6-77.9%), and the 25-year VT-free survival rate after MI was 28.5% (95% CI 15.4-46.5%). The postinfarction left ventricular ejection fraction (LVEF) was related to the outcome in this population (hazard ratio 0.86; 95% CI 0.75-0.95; P=0.002), whereas the development of VT was related to the post-LVEF and to perfusion abnormalities in MPI (P=0.0002). The 30-year survival rate after MI was poor for the patients with a low LVEF. With aging, the existence of nonviable myocardium in the infarct area can induce fatal ventricular arrhythmia more than 10years after the original MI. Springer Science+Business Media, LLC, 2010 Acute myocardial infarction nationallicence Kawasaki disease nationallicence Myocardial perfusion imaging nationallicence Sudden death nationallicence Thrombolysis nationallicence Ventricular tachycardia nationallicence Tsuda Etsuko Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut Hirata Takuya Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut Matsuo Osamu Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut Abe Tadaaki Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut Sugiyama Hisashi Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut Yamada Osamu Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut Pediatric Cardiology Springer-Verlag 32/2(2011-02-01), 176-182 0172-0643 32:2<176 2011 32 246 https://doi.org/10.1007/s00246-010-9838-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00246-010-9838-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tsuda Etsuko Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut NATIONALLICENCE 700 1- Hirata Takuya Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut NATIONALLICENCE 700 1- Matsuo Osamu Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut NATIONALLICENCE 700 1- Abe Tadaaki Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut NATIONALLICENCE 700 1- Sugiyama Hisashi Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut NATIONALLICENCE 700 1- Yamada Osamu Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishirodai, Suita-shi, 565-8565, Osaka, Japan aut NATIONALLICENCE 773 0- Pediatric Cardiology Springer-Verlag 32/2(2011-02-01), 176-182 0172-0643 32:2<176 2011 32 246 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer