caa a22 4500 445831731 CHVBK 20180317145317.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s00586-011-1722-9 doi (NATIONALLICENCE)springer-10.1007/s00586-011-1722-9 Comparison between single- and multi-level patients: clinical and radiological outcomes 2years after cervical disc replacement [Elektronische Daten] [J. Huppert, J. Beaurain, J. Steib, P. Bernard, T. Dufour, I. Hovorka, J. Stecken, P. Dam-Hieu, J. Fuentes, J. Vital, T. Vila, L. Aubourg] In cervical multi-level degenerative pathology, considering the morbidity of the extensive fusion techniques, some authors advocate for the multilevel disc replacement. This study compared the safety and efficacy of disc replacement with an unconstrained prosthesis in multi- versus single-level patients. A total of 231 patients with cervical degenerative disc disease (DDD) who were treated with cervical disc replacement and completed their 24months follow-up were analyzed prospectively: 175 were treated at one level, 56 at 2 levels or more. Comparison between both groups was based on usual clinical and radiological outcomes [Neck Disability Index (NDI), Visual Analog Scale (VAS), Range of Motion, satisfaction]. Safety assessments, including complication and subsequent surgeries, were also documented and compared. Mean NDI and VAS scores for neck and arm pain were improved in both groups similarly. Improvement of mobility at treated segments was also similar. Nevertheless, in the multi-level group, analgesic use was significantly higher and occurrence of Heterotopic Ossification significantly lower than in the single-level group. Subject satisfaction was nearly equal, as 94.2% of single-level group patients would undergo the surgery again versus 94.5% in the multi-level group. The overall success rate did not differ significantly. Multi-level DDD is a challenging indication in the cervical spine. This study showed no major significant clinical difference between the two groups. We need further studies to know more about the impact of multi-level arthroplasty, especially on the adjacent segments, but these results demonstrate initial safety and effectiveness in this patient sample. Springer-Verlag, 2011 Multi-level degenerative disc disease nationallicence Cervical disc replacement nationallicence Clinical study nationallicence Unconstrained cervical disc prosthesis nationallicence Huppert J. Neuro-surgery Department, Clinique du Parc, St-Priest-en-Jarez, France aut Beaurain J. Neuro-surgery Department, University Hospital, Dijon, France aut Steib J. Orthopaedic Surgery Department, University Hospital, Strasbourg, France aut Bernard P. Orthopaedic Surgery Department, Centre Aquitain du Dos, Mérignac, France aut Dufour T. Neuro-surgery Department, Regional Hospital, Orléans, France aut Hovorka I. Orthopaedic Surgery Department, Nice Spine Center, Nice, France aut Stecken J. Neuro-surgery Department, Regional Hospital, Orléans, France aut Dam-Hieu P. Neuro-surgery Department, University Hospital, Brest, France aut Fuentes J. Neuro-surgery Department, Clinique du Millénaire, Montpellier, France aut Vital J. Orthopaedic Surgery Department, University Hospital, Bordeaux, France aut Vila T. LDR Médical, Troyes, France aut Aubourg L. LDR Médical, Troyes, France aut European Spine Journal Springer-Verlag 20/9(2011-09-01), 1417-1426 0940-6719 20:9<1417 2011 20 586 https://doi.org/10.1007/s00586-011-1722-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-011-1722-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Huppert J. Neuro-surgery Department, Clinique du Parc, St-Priest-en-Jarez, France aut NATIONALLICENCE 700 1- Beaurain J. Neuro-surgery Department, University Hospital, Dijon, France aut NATIONALLICENCE 700 1- Steib J. Orthopaedic Surgery Department, University Hospital, Strasbourg, France aut NATIONALLICENCE 700 1- Bernard P. Orthopaedic Surgery Department, Centre Aquitain du Dos, Mérignac, France aut NATIONALLICENCE 700 1- Dufour T. Neuro-surgery Department, Regional Hospital, Orléans, France aut NATIONALLICENCE 700 1- Hovorka I. Orthopaedic Surgery Department, Nice Spine Center, Nice, France aut NATIONALLICENCE 700 1- Stecken J. Neuro-surgery Department, Regional Hospital, Orléans, France aut NATIONALLICENCE 700 1- Dam-Hieu P. Neuro-surgery Department, University Hospital, Brest, France aut NATIONALLICENCE 700 1- Fuentes J. Neuro-surgery Department, Clinique du Millénaire, Montpellier, France aut NATIONALLICENCE 700 1- Vital J. Orthopaedic Surgery Department, University Hospital, Bordeaux, France aut NATIONALLICENCE 700 1- Vila T. LDR Médical, Troyes, France aut NATIONALLICENCE 700 1- Aubourg L. LDR Médical, Troyes, France aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/9(2011-09-01), 1417-1426 0940-6719 20:9<1417 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer