caa a22 4500 445832312 CHVBK 20180317145319.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00586-011-1891-6 doi (NATIONALLICENCE)springer-10.1007/s00586-011-1891-6 Factors determining the success of radiofrequency denervation in lumbar facet joint pain: a prospective study [Elektronische Daten] [Konrad Streitberger, Tina Müller, Urs Eichenberger, Sven Trelle, Michele Curatolo] Background and aims: Radiofrequency denervation (RF) of the lumbar facet joints has been shown to be effective in well-selected patients. However, long-term success varies between studies. We evaluated the influence of selected psychosocial and constitutional factors on the outcome of RF, expressed as the duration of pain relief. Methods: This prospective observational study included 44 patients who received RF denervations at the University Hospital of Berne. Success was defined as at least 50% pain reduction 7-21days, 6months and 1year after RF therapy. The Cox-regression analysis was performed to evaluate the influence of the following factors on the duration of success: age, sex, depression, work inability and previous surgery. Results: Complete follow-up was available for 41 patients. The success rate 7-21days after the denervation was 76%. It decreased to 32% at 6months and to 22% at 1year. The median success duration was 17weeks (95% CI 10-26). The Cox-regression analysis showed a significant shorter duration of success for patients with depression (hazard ratio [HR] 2.97, 95% CI 1.32-6.65), previous surgery (HR 2.39, 95% CI 1.10-5.21) and number of treated joints (HR 1.95 for each increase in the number of joints, 95% CI 1.14-3.33). In bivariate analyses, only depression was kept to be significant. Conclusions: Depression seems to be related with a short duration of success. Based on these findings, a comprehensive study is warranted to evaluate whether psychosocial factors have to be considered when recruiting patients for radiofrequency denervation. Springer-Verlag, 2011 Radiofrequency nationallicence Lumbar facet joint nationallicence Low back pain nationallicence Outcome factors nationallicence Streitberger Konrad Department of Anaesthesiology and Pain Therapy, University Hospital of Bern, Inselspital, 3010, Bern, Switzerland aut Müller Tina Department of Anaesthesiology and Pain Therapy, University Hospital of Bern, Inselspital, 3010, Bern, Switzerland aut Eichenberger Urs Department of Anaesthesiology and Pain Therapy, University Hospital of Bern, Inselspital, 3010, Bern, Switzerland aut Trelle Sven Clinical Trial Unit Bern, Bern University Hospital, Bern, Switzerland aut Curatolo Michele Department of Anaesthesiology and Pain Therapy, University Hospital of Bern, Inselspital, 3010, Bern, Switzerland aut European Spine Journal Springer-Verlag 20/12(2011-12-01), 2160-2165 0940-6719 20:12<2160 2011 20 586 https://doi.org/10.1007/s00586-011-1891-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-011-1891-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Streitberger Konrad Department of Anaesthesiology and Pain Therapy, University Hospital of Bern, Inselspital, 3010, Bern, Switzerland aut NATIONALLICENCE 700 1- Müller Tina Department of Anaesthesiology and Pain Therapy, University Hospital of Bern, Inselspital, 3010, Bern, Switzerland aut NATIONALLICENCE 700 1- Eichenberger Urs Department of Anaesthesiology and Pain Therapy, University Hospital of Bern, Inselspital, 3010, Bern, Switzerland aut NATIONALLICENCE 700 1- Trelle Sven Clinical Trial Unit Bern, Bern University Hospital, Bern, Switzerland aut NATIONALLICENCE 700 1- Curatolo Michele Department of Anaesthesiology and Pain Therapy, University Hospital of Bern, Inselspital, 3010, Bern, Switzerland aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/12(2011-12-01), 2160-2165 0940-6719 20:12<2160 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer