caa a22 4500 445832428 CHVBK 20180317145319.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00586-011-1795-5 doi (NATIONALLICENCE)springer-10.1007/s00586-011-1795-5 Novel biodegradable α-TCP/poly(amino acid) composite artificial lamina following spinal surgery for prevention of intraspinal scar adhesion [Elektronische Daten] [Bo Ran, Yue-Ming Song, Hao Liu, Li-Min Liu, Quan Gong, Tao Li, Jian-Cheng Zeng, Hai-Feng Yuan] Biodegradable copolymer α-TCP/poly(amino acid) composite artificial lamina was prepared and used in goat cervical vertebra resection repair. Cervical 4 was removed by laminectomy, and a vertebra defect of 27×9mm was made. α-TCP/poly(amino acid) composite artificial lamina was inserted in the test group. The efficiency of the copolymer during repair and reconstruction of the goats' vertebra was tested by using X-ray, CT scanning, and histological and biomechanical measurements. In the 24weeks following the operation, the artificial lamina refrained from shifting, and no dural adhesion pressure was observed. In contrast, the control group suffered from infiltration of soft tissue in the spinal canal, dural pressure and α-TCP/poly(amino acid) degradation. In conclusion, α-TCP/poly(amino acid) composite artificial lamina can significantly prevent scar tissue from infiltrating the spinal canal. Springer-Verlag, 2011 Adhesion nationallicence Artificial lamina nationallicence Biodegradable materials nationallicence Cervical nationallicence Ran Bo Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut Song Yue-Ming Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut Liu Hao Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut Liu Li-Min Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut Gong Quan Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut Li Tao Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut Zeng Jian-Cheng Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut Yuan Hai-Feng Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut European Spine Journal Springer-Verlag 20/12(2011-12-01), 2240-2246 0940-6719 20:12<2240 2011 20 586 https://doi.org/10.1007/s00586-011-1795-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-011-1795-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ran Bo Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut NATIONALLICENCE 700 1- Song Yue-Ming Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut NATIONALLICENCE 700 1- Liu Hao Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut NATIONALLICENCE 700 1- Liu Li-Min Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut NATIONALLICENCE 700 1- Gong Quan Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut NATIONALLICENCE 700 1- Li Tao Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut NATIONALLICENCE 700 1- Zeng Jian-Cheng Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut NATIONALLICENCE 700 1- Yuan Hai-Feng Department of Orthopaedic Surgery, The Huaxi Hospital, Si-Chuan University, 37 Waiguoxuexiang, 610041, Sichuan, China aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/12(2011-12-01), 2240-2246 0940-6719 20:12<2240 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer