caa a22 4500 445832487 CHVBK 20180317145319.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00586-011-1878-3 doi (NATIONALLICENCE)springer-10.1007/s00586-011-1878-3 The relevance of intramedullary high signal intensity and gadolinium (Gd-DTPA) enhancement to the clinical outcome in cervical compressive myelopathy [Elektronische Daten] [Yong Cho, Jun Shin, Keun Kim, Dong Chin, Sung Kuh, Ji Lee, Woo Cho] Purpose: We prospectively investigated whether high intramedullary SI and contrast [gadolinium-diethylene-triamine-pentaacetic acid (Gd-DTPA)] enhancement in magnetic resonance imaging (MRI) are associated with postoperative prognosis in cervical compressive myelopathy (CCM) patients. Methods: Seventy-four patients with ventral cord compression at one or two levels underwent anterior cervical discectomy and fusion (ACDF) for CCM between March 2006 and June 2009. The mean follow-up period was 39.7months (range, 12.7-55.7months). The cervical cord compression ratio and clinical outcomes were measured using Japanese Orthopedic Association (JOA) scores for cervical myelopathy. Patients were classified into three groups based on the SI change in T2WI, T1-weighted images (T1WI), and contrast (Gd-DTPA) enhancement. Results: The mean preoperative and postoperative JOA scores were 10.5±2.9 and 15.0±2.1 (P<0.05), respectively. The mean recovery ratio of the JOA score was 70.9±20.2%. There were statistically significant differences in postoperative JOA and recovery ratio among three groups. However, post-surgical neurological outcomes were not associated with age, symptom duration, preoperative JOA, and cord compression. Conclusions: We found that intramedullary SI change is a poor prognostic factor and the intramedullary contrast (Gd-DTPA) enhancement on preoperative MRI should be viewed as the worst predictor of surgical outcomes in cervical myelopathy. Contrast (Gd-DTPA) enhancement and postoperative MRI are useful for identifying the prognosis of patients with poor neurological recovery. Springer-Verlag, 2011 Cervical compressive myelopathy nationallicence Magnetic resonance imaging (MRI) nationallicence Increased signal intensity nationallicence Intramedullary Gd-DTPA enhancement nationallicence Cho Yong Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Spine Hospital, Yonsei University College of Medicine, 146-92, Dogok-Dong, Kangnam-gu, Kangnam, PO Box 1217, 135-720, Seoul, Korea aut Shin Jun Department of Neurosurgery, Sanggye Paik Hospital, Inje University College of Medicine, Sanggye-7 dong, 761-1, Nowon-gu, 139-707, Seoul, Korea aut Kim Keun Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Spine Hospital, Yonsei University College of Medicine, 146-92, Dogok-Dong, Kangnam-gu, Kangnam, PO Box 1217, 135-720, Seoul, Korea aut Chin Dong Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Spine Hospital, Yonsei University College of Medicine, 146-92, Dogok-Dong, Kangnam-gu, Kangnam, PO Box 1217, 135-720, Seoul, Korea aut Kuh Sung Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Spine Hospital, Yonsei University College of Medicine, 146-92, Dogok-Dong, Kangnam-gu, Kangnam, PO Box 1217, 135-720, Seoul, Korea aut Lee Ji Department of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Sanggye-7 dong, 761-1, Nowon-gu, 139-707, Seoul, Korea aut Cho Woo Department of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Sanggye-7 dong, 761-1, Nowon-gu, 139-707, Seoul, Korea aut European Spine Journal Springer-Verlag 20/12(2011-12-01), 2267-2274 0940-6719 20:12<2267 2011 20 586 https://doi.org/10.1007/s00586-011-1878-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-011-1878-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cho Yong Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Spine Hospital, Yonsei University College of Medicine, 146-92, Dogok-Dong, Kangnam-gu, Kangnam, PO Box 1217, 135-720, Seoul, Korea aut NATIONALLICENCE 700 1- Shin Jun Department of Neurosurgery, Sanggye Paik Hospital, Inje University College of Medicine, Sanggye-7 dong, 761-1, Nowon-gu, 139-707, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Keun Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Spine Hospital, Yonsei University College of Medicine, 146-92, Dogok-Dong, Kangnam-gu, Kangnam, PO Box 1217, 135-720, Seoul, Korea aut NATIONALLICENCE 700 1- Chin Dong Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Spine Hospital, Yonsei University College of Medicine, 146-92, Dogok-Dong, Kangnam-gu, Kangnam, PO Box 1217, 135-720, Seoul, Korea aut NATIONALLICENCE 700 1- Kuh Sung Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Spine Hospital, Yonsei University College of Medicine, 146-92, Dogok-Dong, Kangnam-gu, Kangnam, PO Box 1217, 135-720, Seoul, Korea aut NATIONALLICENCE 700 1- Lee Ji Department of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Sanggye-7 dong, 761-1, Nowon-gu, 139-707, Seoul, Korea aut NATIONALLICENCE 700 1- Cho Woo Department of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Sanggye-7 dong, 761-1, Nowon-gu, 139-707, Seoul, Korea aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/12(2011-12-01), 2267-2274 0940-6719 20:12<2267 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer