caa a22 4500 445832517 CHVBK 20180317145320.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00586-011-1834-2 doi (NATIONALLICENCE)springer-10.1007/s00586-011-1834-2 Dual pathology as a result of spinal stenosis and vitamin B12 deficiency [Elektronische Daten] [Mohammed Patel, Zurqa Rasul, Philip Sell] Vitamin B12 deficiency can confound the clinical assessment of patients presenting with features of spinal disorders. Speciality practice within spinal surgery may lead the clinician to a focus upon spinal explanations for symptoms and that belief may be reinforced by supporting imaging. In the presence of mainly sensory symptoms consideration and exclusion of non surgical causes needs to occur. This study aimed at identifying the prevalence of vitamin B12 deficiency; the presence of dual pathology on imaging performed; the implementation of replacement therapy and their subsequent clinical response as perceived by patients. This was performed through a retrospective review of patients presenting to specialist spine out-patient clinics over a 4-year period via access to pathology reports followed by a telephone survey. 457 patients were investigated of which 8.5% were vitamin B12 deficient. 70% of patients had repeat levels and 31% continued to be deficient. 26% of these patients were not placed on any supplemental therapy. 72% of patients on treatment had self perceived improved outcomes as compared with 55% not on treatment. 73% of patients underwent MRI/CT imaging. 59% of which had evidence of spinal stenosis. In older patients with sensory symptoms, the coexistence of B12 deficiency should be considered. Detection of deficiency with consequent treatment results in better global outcomes than no treatment. Unless the correct blood test is done, the pathology will remain undetected, and patients may continue with their primary symptoms despite high-risk spinal surgical procedures. Springer-Verlag, 2011 Spinal stenosis nationallicence Vitamin B12 nationallicence Peripheral neuropathy nationallicence Dysaesthesia nationallicence Coexisting pathologies nationallicence Patel Mohammed Orthopaedic Department, Leicester General Hospital, Gwendelon Road, LE5 4PW, Leicester, UK aut Rasul Zurqa Orthopaedic Department, Leicester General Hospital, Gwendelon Road, LE5 4PW, Leicester, UK aut Sell Philip Orthopaedic Department, Leicester General Hospital, Gwendelon Road, LE5 4PW, Leicester, UK aut European Spine Journal Springer-Verlag 20/12(2011-12-01), 2247-2251 0940-6719 20:12<2247 2011 20 586 https://doi.org/10.1007/s00586-011-1834-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-011-1834-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Patel Mohammed Orthopaedic Department, Leicester General Hospital, Gwendelon Road, LE5 4PW, Leicester, UK aut NATIONALLICENCE 700 1- Rasul Zurqa Orthopaedic Department, Leicester General Hospital, Gwendelon Road, LE5 4PW, Leicester, UK aut NATIONALLICENCE 700 1- Sell Philip Orthopaedic Department, Leicester General Hospital, Gwendelon Road, LE5 4PW, Leicester, UK aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/12(2011-12-01), 2247-2251 0940-6719 20:12<2247 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer