caa a22 4500 445832541 CHVBK 20180317145320.0 cr unu---uuuuu 170323e20111201xx s 000 0 eng 10.1007/s00586-011-1838-y doi (NATIONALLICENCE)springer-10.1007/s00586-011-1838-y Spinal epidural abscess: aetiology, predisponent factors and clinical outcomes in a 4-year prospective study [Elektronische Daten] [Stephan Zimmerer, Anna Conen, Andreas Müller, Martin Sailer, Ethan Taub, Ursula Flückiger, Katja Schwenzer-Zimmerer] Spinal epidural abscess (SEA) is a rare, but serious, condition with multiple causes. We prospectively studied the aetiology, predisposing factors, and clinical outcomes of SEA in all patients with SEA treated in our hospital's neurosurgical service from 2004 to 2008. For each patient, we recorded the medical history, comorbidities, focus of infection, pathogen(s), and outcome. The 36 patients (19 women and 17 men) ranged in age from 34 to 80years old (mean 57; median 56). The SEA was primary (i.e., due to haematogenous spread) in 16 patients (44%); it was secondary to elective spinal procedures, either injections or surgery, in 20 patients (56%). The duration of follow-up was 12-60months (mean 36; median 37.5). The most common pathogen, Staphylococcus aureus, was found in 18 patients (50%). Patients with primary SEA had different underlying diseases and a wider range of pathogens than those with secondary SEA. Only five patients (14%) had no major comorbidity; 16 of the 20 patients with secondary SEA (44% of the overall group) had undergone spinal surgery before developing the SEA; the treatment of the SEA involved multiple surgical operations in all 16 of these patients, and spinal instrumentation in 5 (14%); 22 patients (61% of the overall group) recovered fully. Springer-Verlag, 2011 Spinal epidural abscess (SEA) nationallicence Surgical site infection (SSI) nationallicence Focal infection nationallicence Staphylococcus aureus nationallicence Instrumented surgery nationallicence Zimmerer Stephan Department of Neurosurgery, University Hospital Basel, Basel University, Spitalstrasse 21, 4031, Basel, Switzerland aut Conen Anna Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Petersgraben 41, 4031, Basel, Switzerland aut Müller Andreas Hightech Research Centre of CMF-Surgery, Research Collaboration Clinical Morphology and Biomedical Engineering (CMBE), Basel University, Schanzenstrasse 46, 4031, Basel, Switzerland aut Sailer Martin Department of Neurosurgery, University Hospital Basel, Basel University, Spitalstrasse 21, 4031, Basel, Switzerland aut Taub Ethan Department of Neurosurgery, University Hospital Basel, Basel University, Spitalstrasse 21, 4031, Basel, Switzerland aut Flückiger Ursula Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Petersgraben 41, 4031, Basel, Switzerland aut Schwenzer-Zimmerer Katja Hightech Research Centre of CMF-Surgery, Research Collaboration Clinical Morphology and Biomedical Engineering (CMBE), Basel University, Schanzenstrasse 46, 4031, Basel, Switzerland aut European Spine Journal Springer-Verlag 20/12(2011-12-01), 2228-2234 0940-6719 20:12<2228 2011 20 586 https://doi.org/10.1007/s00586-011-1838-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-011-1838-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zimmerer Stephan Department of Neurosurgery, University Hospital Basel, Basel University, Spitalstrasse 21, 4031, Basel, Switzerland aut NATIONALLICENCE 700 1- Conen Anna Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Petersgraben 41, 4031, Basel, Switzerland aut NATIONALLICENCE 700 1- Müller Andreas Hightech Research Centre of CMF-Surgery, Research Collaboration Clinical Morphology and Biomedical Engineering (CMBE), Basel University, Schanzenstrasse 46, 4031, Basel, Switzerland aut NATIONALLICENCE 700 1- Sailer Martin Department of Neurosurgery, University Hospital Basel, Basel University, Spitalstrasse 21, 4031, Basel, Switzerland aut NATIONALLICENCE 700 1- Taub Ethan Department of Neurosurgery, University Hospital Basel, Basel University, Spitalstrasse 21, 4031, Basel, Switzerland aut NATIONALLICENCE 700 1- Flückiger Ursula Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Petersgraben 41, 4031, Basel, Switzerland aut NATIONALLICENCE 700 1- Schwenzer-Zimmerer Katja Hightech Research Centre of CMF-Surgery, Research Collaboration Clinical Morphology and Biomedical Engineering (CMBE), Basel University, Schanzenstrasse 46, 4031, Basel, Switzerland aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/12(2011-12-01), 2228-2234 0940-6719 20:12<2228 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer