caa a22 4500 445832622 CHVBK 20180317145320.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s00586-010-1587-3 doi (NATIONALLICENCE)springer-10.1007/s00586-010-1587-3 Diffusion tensor imaging in the cervical spinal cord [Elektronische Daten] [Ting Song, Wen-Jun Chen, Bo Yang, Hong-Pu Zhao, Jian-Wei Huang, Ming-Jin Cai, Tian-Fa Dong, Tang-Sheng Li] There are discrepancy between MR findings and clinical presentations. The compressed cervical cord in patients of the spondylotic myelopathy may be normal on conventional MRI when it is at the earlier stage or even if patients had severe symptoms. Therefore, it is necessary to take a developed MR technique—diffusion tensor imaging (DTI)—to detect the intramedullary lesions. Prospective MR and DTI were performed in 53 patients with cervical compressive myelopathy and twenty healthy volunteers. DTI was performed along six non-collinear directions with single-shot spin echo echo-planar imaging (EPI) sequence. Intramedullary apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values were measured in four segments (C2/3, C3/4, C4/5, C5/6) for volunteers, in lesions (or the compressed cord) and normal cord for patients. DTI original images were processed to produce color DTI maps. In the volunteers' group, cervical cord exhibited blue on the color DTI map. FA values between four segments had a significant difference (P<0.01), with the highest FA value (0.85±0.03) at C2/3 level. However, ADC value between them had no significant difference (P>0.05). For patients, only 24 cases showed hyperintense on T2-weighted image, while 39 cases shown patchy green signal on color DTI maps. ADC and FA values between lesions or the compressed cord and normal spinal cord of patients had a significant difference (both P<0.01). FA value at C2/3 cord is the highest of other segments and it gradually decreases towards the caudal direction. Using single-shot spin echo EPI sequence and six non-collinear diffusion directions with b value of 400smm−2, DTI can clearly show the intramedullary microstructure and more lesions than conventional MRI. Springer-Verlag, 2010 MR nationallicence Diffusion tensor imaging (DTI) nationallicence Cervical myelopathy nationallicence Apparent diffusion coefficient (ADC) nationallicence Fractional anisotropy (FA) nationallicence Song Ting Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut Chen Wen-Jun Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut Yang Bo Department of Orthopedics, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut Zhao Hong-Pu Department of Orthopedics, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut Huang Jian-Wei Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut Cai Ming-Jin Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut Dong Tian-Fa Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut Li Tang-Sheng Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut European Spine Journal Springer-Verlag 20/3(2011-03-01), 422-428 0940-6719 20:3<422 2011 20 586 https://doi.org/10.1007/s00586-010-1587-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-010-1587-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Song Ting Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut NATIONALLICENCE 700 1- Chen Wen-Jun Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut NATIONALLICENCE 700 1- Yang Bo Department of Orthopedics, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut NATIONALLICENCE 700 1- Zhao Hong-Pu Department of Orthopedics, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut NATIONALLICENCE 700 1- Huang Jian-Wei Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut NATIONALLICENCE 700 1- Cai Ming-Jin Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut NATIONALLICENCE 700 1- Dong Tian-Fa Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut NATIONALLICENCE 700 1- Li Tang-Sheng Department of Radiology, The Third Affiliated Hospital of Guangzhou Medical University, No. 63 Duobao Road, 510150, Guangdong, Guangzhou, China aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/3(2011-03-01), 422-428 0940-6719 20:3<422 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer