caa a22 4500 445833807 CHVBK 20180317145324.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00586-010-1497-4 doi (NATIONALLICENCE)springer-10.1007/s00586-010-1497-4 Anatomical and surgical study of volume determination of the anterolateral epidural space nerve root L5/S1 under the aspect of epidural perineural injection in minimal invasive treatment of lumbar nerve root compression [Elektronische Daten] [Wolfram Teske, Sonja Zirke, Jan Nottenkämper, Thomas Lichtinger, Theodoros Theodoridis, Jürgen Krämer, Klaus Schmidt] Herniated intervertebral disc causes in a great number of cases of lumbar nerve root compression, especially in the segment L5/S1. Other reasons responsible for stress to the lumbar spinal root are the spinal canal stenosis and the postdiscotomy syndrome. For patients without neurological deficiencies, the conservative treatment includes different epidural injection techniques. Steroids are often applied. A specific injection technique needing only a small drug amount is the epidural perineural approach using a special two-needle technique. The anatomical spaces of the nerve roots have received little attention in therapy. We have determined the anterolateral epidural space nerve volume of the nerve root L5/S1, and compared the data collected in an anatomical study with operative measurements during discectomy. The volume determination in the human cadavers was performed with liquid silicone filling the anterolateral space after dissection. The in vivo measurements were performed during surgery at the site of the anterolateral space after discectomy. The anatomical studies showed us a mean value volume of 1.1ml. The surgical volume determinations result in a mean volume of 0.9ml. A better understanding of the anterolateral epidural space may allow a reduction of the injection volume in the conservative nerve root compression treatment, especially using the epidural perineural technique, avoiding the risk of side effects of high doses of steroids. The Author(s), 2010 Lumbar nerve root compression nationallicence Anatomical volume determination nationallicence Epidural-perineural injection technique nationallicence Teske Wolfram Orthopädische Universitätsklinik am St. Josef Hospital, Ruhr Universität Bochum, Gudrunstrasse 56, 44791, Bochum, Germany aut Zirke Sonja Institut für Wirbelsäulenforschung an der Ruhr Universität Bochum, Viktoriastr. 66-70, 44787, Bochum, Germany aut Nottenkämper Jan Orthopädische Universitätsklinik am St. Josef Hospital, Ruhr Universität Bochum, Gudrunstrasse 56, 44791, Bochum, Germany aut Lichtinger Thomas Orthopädische Universitätsklinik am St. Josef Hospital, Ruhr Universität Bochum, Gudrunstrasse 56, 44791, Bochum, Germany aut Theodoridis Theodoros Institut für Wirbelsäulenforschung an der Ruhr Universität Bochum, Viktoriastr. 66-70, 44787, Bochum, Germany aut Krämer Jürgen Institut für Wirbelsäulenforschung an der Ruhr Universität Bochum, Viktoriastr. 66-70, 44787, Bochum, Germany aut Schmidt Klaus Kath. Krankenhaus Dortmund-West, Zollernstrasse 40, 44379, Dortmund, Germany aut European Spine Journal Springer-Verlag 20/4(2011-04-01), 537-541 0940-6719 20:4<537 2011 20 586 https://doi.org/10.1007/s00586-010-1497-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-010-1497-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Teske Wolfram Orthopädische Universitätsklinik am St. Josef Hospital, Ruhr Universität Bochum, Gudrunstrasse 56, 44791, Bochum, Germany aut NATIONALLICENCE 700 1- Zirke Sonja Institut für Wirbelsäulenforschung an der Ruhr Universität Bochum, Viktoriastr. 66-70, 44787, Bochum, Germany aut NATIONALLICENCE 700 1- Nottenkämper Jan Orthopädische Universitätsklinik am St. Josef Hospital, Ruhr Universität Bochum, Gudrunstrasse 56, 44791, Bochum, Germany aut NATIONALLICENCE 700 1- Lichtinger Thomas Orthopädische Universitätsklinik am St. Josef Hospital, Ruhr Universität Bochum, Gudrunstrasse 56, 44791, Bochum, Germany aut NATIONALLICENCE 700 1- Theodoridis Theodoros Institut für Wirbelsäulenforschung an der Ruhr Universität Bochum, Viktoriastr. 66-70, 44787, Bochum, Germany aut NATIONALLICENCE 700 1- Krämer Jürgen Institut für Wirbelsäulenforschung an der Ruhr Universität Bochum, Viktoriastr. 66-70, 44787, Bochum, Germany aut NATIONALLICENCE 700 1- Schmidt Klaus Kath. Krankenhaus Dortmund-West, Zollernstrasse 40, 44379, Dortmund, Germany aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/4(2011-04-01), 537-541 0940-6719 20:4<537 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer