caa a22 4500 445833823 CHVBK 20180317145324.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s00586-010-1568-6 doi (NATIONALLICENCE)springer-10.1007/s00586-010-1568-6 Posterior lumbar interbody fusion using non resorbable poly-ether-ether-ketone versus resorbable poly- l -lactide-co- d , l -lactide fusion devices. Clinical outcome at a minimum of 2-year follow-up [Elektronische Daten] [Timothy Jiya, T. Smit, B. van Royen, M. Mullender] Previous papers on resorbable poly-l-lactide-co-d,l-lactide (PLDLLA) cages in spinal fusion have failed to report adequately on patient-centred clinical outcome measures. Also comparison of PLDLLA cage with a traditionally applicable counterpart has not been previously reported. This is the first randomized prospective study that assesses clinical outcome of PLDLLA cage compared with a poly-ether-ether-ketone (PEEK) implant. Twenty-six patients were randomly assigned to undergo instrumented posterior lumbar interbody fusion (PLIF) whereby either a PEEK cage or a PLDLLA cage was implanted. Clinical outcome based on visual analogue scale scores for leg pain and back pain, as well as Oswestry Disability Index (ODI) and SF-36 questionnaires were documented and analysed. When compared with preoperative values, all clinical parameters have significantly improved in the PEEK group at 2years after surgery with the exception of SF-36 general health, SF-36 mental health and SF-36 role emotional scores. No clinical parameter showed significant improvement at 2years after surgery compared with preoperative values in the PLDLLA patient group. Only six patients (50%) in the PLDLLA group showed improvement in the VAS scores for leg and back pain as well as the ODI, as opposed to 10 patients (71%) in the PEEK group. One-third of the patients in the PLDLLA group actually reported worsening of their pain scores and ODI. Three cases of mild to moderate osteolysis were seen in the PLDLLA group. Following up on our preliminary report, these 2-year results confirm the superiority of the PEEK implant to the resorbable PLDLLA implant in aiding spinal fusion and alleviating symptoms following PLIF in patients with degenerative spondylolisthesis associated with either canal stenosis or foramen stenosis or both and emanating from a single lumbar segment. The Author(s), 2010 Lumbar interbody fusion nationallicence PEEK cage nationallicence PLDLLA nationallicence Resorbable cage nationallicence Jiya Timothy Department of Orthopaedic Surgery, VU University Medical Centre and the Skeletal Tissue Engineering Group, De Boelelaan 1117, Postbus 7057, 1007 MB, Amsterdam, The Netherlands aut Smit T. Department of Orthopaedic Surgery, VU University Medical Centre and the Skeletal Tissue Engineering Group, De Boelelaan 1117, Postbus 7057, 1007 MB, Amsterdam, The Netherlands aut van Royen B. Department of Orthopaedic Surgery, VU University Medical Centre and the Skeletal Tissue Engineering Group, De Boelelaan 1117, Postbus 7057, 1007 MB, Amsterdam, The Netherlands aut Mullender M. Department of Orthopaedic Surgery, VU University Medical Centre and the Skeletal Tissue Engineering Group, De Boelelaan 1117, Postbus 7057, 1007 MB, Amsterdam, The Netherlands aut European Spine Journal Springer-Verlag 20/4(2011-04-01), 618-622 0940-6719 20:4<618 2011 20 586 https://doi.org/10.1007/s00586-010-1568-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-010-1568-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jiya Timothy Department of Orthopaedic Surgery, VU University Medical Centre and the Skeletal Tissue Engineering Group, De Boelelaan 1117, Postbus 7057, 1007 MB, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Smit T. Department of Orthopaedic Surgery, VU University Medical Centre and the Skeletal Tissue Engineering Group, De Boelelaan 1117, Postbus 7057, 1007 MB, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- van Royen B. Department of Orthopaedic Surgery, VU University Medical Centre and the Skeletal Tissue Engineering Group, De Boelelaan 1117, Postbus 7057, 1007 MB, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Mullender M. Department of Orthopaedic Surgery, VU University Medical Centre and the Skeletal Tissue Engineering Group, De Boelelaan 1117, Postbus 7057, 1007 MB, Amsterdam, The Netherlands aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/4(2011-04-01), 618-622 0940-6719 20:4<618 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer