caa a22 4500 445834013 CHVBK 20180317145324.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00586-011-1738-1 doi (NATIONALLICENCE)springer-10.1007/s00586-011-1738-1 Comparison of polymethylmethacrylate versus expandable cage in anterior vertebral column reconstruction after posterior extracavitary corpectomy in lumbar and thoraco-lumbar metastatic spine tumors [Elektronische Daten] [Mohammed Eleraky, Ioannis Papanastassiou, Nam Tran, Elias Dakwar, Frank Vrionis] Single-stage posterior corpectomy for the management of spinal tumors has been well described. Anterior column reconstruction has been accomplished using polymethylmethacrylate (PMMA) or expandable cages (EC). The aim of this retrospective study was to compare PMMA versus ECs in anterior vertebral column reconstruction after posterior corpectomy for tumors in the lumbar and thoracolumbar spine. Between 2006 and 2009 we identified 32 patients that underwent a single-stage posterior extracavitary tumor resection and anterior reconstruction, 16 with PMMA and 16 with EC. There were no baseline differences in regards to age (mean: 58.2years) or performance status. Differences between groups in terms of survival, estimated blood loss (EBL), kyphosis reduction (decrease in Cobb's angle), pain, functional outcomes, and performance status were evaluated. Mean overall survival and EBL were 17months and 1165ml, respectively. No differences were noted between the study groups in regards to survival (p=0.5) or EBL (p=0.8). There was a trend for better Kyphosis reduction in favor of the EC group (10.04 vs. 5.45, p=0.16). No difference in performance status or VAS improvements was observed (p>0.05). Seven patients had complications that led to reoperation (5 infections). PMMA or ECs are viable options for reconstruction of the anterior vertebral column following tumor resection and corpectomy. Both approaches allow for correction of the kyphotic deformity, and stabilization of the anterior vertebral column with similar functional and performance status outcomes in the lumbar and thoracolumbar area. Springer-Verlag, 2011 Spine metastasis nationallicence Polymethylmethacrylate nationallicence Expandable cage nationallicence Posterolateral approach nationallicence ASIA : American Spinal Injury Association nationallicence ECOG : Eastern Cooperative Oncology Group nationallicence KPS : Karnofsky performance status nationallicence ESCC : Epidural spinal cord compression nationallicence PTA : Posterolateral transpedicular approach nationallicence EC : Expandable cage nationallicence PMMA : Polymethylmethacrylate nationallicence VAS : Visual analog scale nationallicence MR : Magnetic resonance nationallicence Eleraky Mohammed H. Lee Moffitt Cancer Center & Research Institute, NeuroOncology Program and Department of Neurosurgery, University of South Florida College of Medicine, 12902 Magnolia Drive, 33647, Tampa, FL, USA aut Papanastassiou Ioannis H. Lee Moffitt Cancer Center & Research Institute, NeuroOncology Program and Department of Neurosurgery, University of South Florida College of Medicine, 12902 Magnolia Drive, 33647, Tampa, FL, USA aut Tran Nam H. Lee Moffitt Cancer Center & Research Institute, NeuroOncology Program and Department of Neurosurgery, University of South Florida College of Medicine, 12902 Magnolia Drive, 33647, Tampa, FL, USA aut Dakwar Elias H. Lee Moffitt Cancer Center & Research Institute, NeuroOncology Program and Department of Neurosurgery, University of South Florida College of Medicine, 12902 Magnolia Drive, 33647, Tampa, FL, USA aut Vrionis Frank H. Lee Moffitt Cancer Center & Research Institute, NeuroOncology Program and Department of Neurosurgery, University of South Florida College of Medicine, 12902 Magnolia Drive, 33647, Tampa, FL, USA aut European Spine Journal Springer-Verlag 20/8(2011-08-01), 1363-1370 0940-6719 20:8<1363 2011 20 586 https://doi.org/10.1007/s00586-011-1738-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-011-1738-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Eleraky Mohammed H. Lee Moffitt Cancer Center & Research Institute, NeuroOncology Program and Department of Neurosurgery, University of South Florida College of Medicine, 12902 Magnolia Drive, 33647, Tampa, FL, USA aut NATIONALLICENCE 700 1- Papanastassiou Ioannis H. Lee Moffitt Cancer Center & Research Institute, NeuroOncology Program and Department of Neurosurgery, University of South Florida College of Medicine, 12902 Magnolia Drive, 33647, Tampa, FL, USA aut NATIONALLICENCE 700 1- Tran Nam H. Lee Moffitt Cancer Center & Research Institute, NeuroOncology Program and Department of Neurosurgery, University of South Florida College of Medicine, 12902 Magnolia Drive, 33647, Tampa, FL, USA aut NATIONALLICENCE 700 1- Dakwar Elias H. Lee Moffitt Cancer Center & Research Institute, NeuroOncology Program and Department of Neurosurgery, University of South Florida College of Medicine, 12902 Magnolia Drive, 33647, Tampa, FL, USA aut NATIONALLICENCE 700 1- Vrionis Frank H. Lee Moffitt Cancer Center & Research Institute, NeuroOncology Program and Department of Neurosurgery, University of South Florida College of Medicine, 12902 Magnolia Drive, 33647, Tampa, FL, USA aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/8(2011-08-01), 1363-1370 0940-6719 20:8<1363 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer