caa a22 4500 445834099 CHVBK 20180317145325.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00586-011-1705-x doi (NATIONALLICENCE)springer-10.1007/s00586-011-1705-x Vertebroplasty: benefits are more than risks in selected and evidence-based informed patients. A retrospective study of 59 cases [Elektronische Daten] [Giovanni Brodano, Luca Amendola, Konstantinos Martikos, Camilla Bettuzzi, Luca Boriani, Alessandro Gasbarrini, Stefano Bandiera, Silvia Terzi, Tiziana Greggi, Stefano Boriani] Vertebral compression fractures represent a frequent pathology among elderly population, with potentially devastating consequences. More than 20years have passed since percutaneous vertebroplasty was initially used in the treatment of angiomas, representing nowadays a widely used treatment for osteoporotic vertebral fractures. The authors present a retrospective review of 59 consecutive patients (in total 94 fractured levels) that underwent polymethylmethacrylate percutaneous vertebroplasty for vertebral compression fractures due to senile or secondary osteoporosis. All fractures were free from neurologic involvement and were classified as A1 type according to Magerl classification. All of patients were initially treated conservatively, by application of orthosis that allows immediate deambulation. At control, patients who complained of pain and limitation of daily activities underwent MRI. If presence of marrow signal changes, especially hypertense signal in T2-weighted images was confirmed, percutaneous vertebroplasty procedure was performed (we could call it "sub-acute” procedure). A limited group of patients that did not tolerate brace and had an insufficient pain control underwent vertebroplasty "in acute”, few days after fracture. Immediate post-operative pain reduction and follow-up clinical outcome (estimating quality of life and residual back pain) were evaluated by means of Visual Analogue Scale, SF-36 and Oswestry Disability Index. In the immediate post-operative course a significant pain relief was found in 39 patients (66.1%), moderate pain relief in 17 (28.8%), while 3 (5.1%) did not achieve relevant pain improvement. Pain intensity and life quality was maintained within satisfactory limits after a mean follow-up of 16months. In conclusion, percutaneous vertebroplasty is an effective and safe procedure for treating vertebral compression fractures in the elderly. It provides immediate pain relief and allows early mobilization, thus avoiding potentially severe complications related to persistent back pain and prolonged bed rest. When performed by experienced surgeon complication rate is low, representing a safe procedure, able to provide a satisfactory outcome. Springer-Verlag, 2011 Percutaneous vertebroplasty nationallicence Vertebral compression fractures nationallicence Osteoporosis nationallicence Pain nationallicence Quality of life nationallicence Brodano Giovanni Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut Amendola Luca Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut Martikos Konstantinos Department of Spinal Deformities Surgery, Rizzoli Institute, Bologna, Italy aut Bettuzzi Camilla Department of Pediatric Orthopedics and Traumatology, Rizzoli Institute, Bologna, Italy aut Boriani Luca Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut Gasbarrini Alessandro Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut Bandiera Stefano Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut Terzi Silvia Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut Greggi Tiziana Department of Spinal Deformities Surgery, Rizzoli Institute, Bologna, Italy aut Boriani Stefano Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut European Spine Journal Springer-Verlag 20/8(2011-08-01), 1265-1271 0940-6719 20:8<1265 2011 20 586 https://doi.org/10.1007/s00586-011-1705-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-011-1705-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Brodano Giovanni Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Amendola Luca Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Martikos Konstantinos Department of Spinal Deformities Surgery, Rizzoli Institute, Bologna, Italy aut NATIONALLICENCE 700 1- Bettuzzi Camilla Department of Pediatric Orthopedics and Traumatology, Rizzoli Institute, Bologna, Italy aut NATIONALLICENCE 700 1- Boriani Luca Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Gasbarrini Alessandro Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Bandiera Stefano Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Terzi Silvia Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Greggi Tiziana Department of Spinal Deformities Surgery, Rizzoli Institute, Bologna, Italy aut NATIONALLICENCE 700 1- Boriani Stefano Department of Oncological and Degenerative Spine Surgery, Rizzoli Institute, via Pupilli 1, 40136, Bologna, Italy aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/8(2011-08-01), 1265-1271 0940-6719 20:8<1265 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer