caa a22 4500 445834218 CHVBK 20180317145325.0 cr unu---uuuuu 170323e20110801xx s 000 0 eng 10.1007/s00586-011-1831-5 doi (NATIONALLICENCE)springer-10.1007/s00586-011-1831-5 In vivo preclinical evaluation of the influence of osteoporosis on the anchorage of different pedicle screw designs [Elektronische Daten] [Gianluca Giavaresi, Milena Fini, Roberto Giardino, Francesca Salamanna, Maria Sartori, Veronica Borsari, Silvia Spriano, Chiara Bellini, Marco Brayda-Bruno] We investigate the anchorage of pedicle screws with different surface treatments in osteoporotic bone. Eight ewes were divided into two groups of four animals each: four sheep underwent bilateral ovariectomy (OVX Group), whereas the operation was simulated in the remaining group (SHAM Group). Eighteen months after the first operation, the Dynesys® System was fitted to the sheep using pedicle screws with three different surface treatments: untreated, rough blasted (uncoated) and bioactive coated (bioactive). Uncoated screws showed a significantly higher bone ingrowth value compared with the untreated screws in the OVX group (9.3%, p<0.005) and a significantly lower bone ingrowth value in the SHAM group (−11.0%, p<0.05). Furthermore, the bioactive pedicle screws had a significant lower bone ingrowth value than the untreated screws in the SHAM group (−12.1%, p<0.05). These results suggest that both tested surface treatments of pedicular screws may provide an advantage in terms of bone quality and osseointegration, when implanted in osteoporotic vertebrae. Springer-Verlag, 2011 Pedicle screws nationallicence Surface treatment nationallicence Osteoporosis nationallicence Osseointegration nationallicence Giavaresi Gianluca Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut Fini Milena Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut Giardino Roberto Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut Salamanna Francesca Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut Sartori Maria Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut Borsari Veronica Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut Spriano Silvia DISMIC Department, Politecnico di Torino, C.so Duca degli Abruzzi 24, 10129, Turin, Italy aut Bellini Chiara IRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161, Milan, Italy aut Brayda-Bruno Marco IRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161, Milan, Italy aut European Spine Journal Springer-Verlag 20/8(2011-08-01), 1289-1296 0940-6719 20:8<1289 2011 20 586 https://doi.org/10.1007/s00586-011-1831-5 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-011-1831-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Giavaresi Gianluca Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Fini Milena Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Giardino Roberto Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Salamanna Francesca Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Sartori Maria Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Borsari Veronica Laboratory of Preclinical and Surgical Studies, Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136, Bologna, Italy aut NATIONALLICENCE 700 1- Spriano Silvia DISMIC Department, Politecnico di Torino, C.so Duca degli Abruzzi 24, 10129, Turin, Italy aut NATIONALLICENCE 700 1- Bellini Chiara IRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161, Milan, Italy aut NATIONALLICENCE 700 1- Brayda-Bruno Marco IRCCS Istituto Ortopedico Galeazzi, Via R. Galeazzi 4, 20161, Milan, Italy aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/8(2011-08-01), 1289-1296 0940-6719 20:8<1289 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer