caa a22 4500 445834285 CHVBK 20180317145325.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s00586-010-1591-7 doi (NATIONALLICENCE)springer-10.1007/s00586-010-1591-7 Operative treatment of isthmic spondylolisthesis in children: a long-term, retrospective comparative study with matched cohorts [Elektronische Daten] [Tuomas Jalanko, Ilkka Helenius, Ville Remes, Tommi Lamberg, Pekka Tervahartiala, Timo Yrjönen, Mikko Poussa, Dietrich Schlenzka] The purpose of the present study was to compare the long-term clinical, functional and radiographic outcomes of young patients operated on before or at the onset of puberty (Children) and those operated on after that (Adolescents). The study group consisted of 298 patients operated on under the age of 20years; 55 of them were operated on before or at the onset of growth spurt (29 females <12.5 years, 26 males <14.5 years). Preoperative data were retrieved from patients' records. After mean follow-up of 17years (10.7-26.3), physical examination, radiographic measurements and functional testing were performed by independent observers. SRS-24, Oswestry Disability Index (ODI), and Visual Analogue Scale (VAS) were utilised to evaluate health-related quality of life. The data were compared between the two age groups in the whole study population and in 41 pairs of patients matched by gender, operative method, severity of preoperative slip, and age at follow-up. Preoperatively, one-third of children did not have significant pain symptoms. They were operated upon for resistant postural anomalies in combination with high risk of slip progression. All of the adolescents had low-back pain as the main clinical symptom. The outcomes were satisfactory in both groups in the whole population (children vs. adolescents; low-grade slip: SRS-24: 95.9 vs. 92.0, ODI: 5.2 vs. 7.5, VAS low-back pain: 18.9 vs. 21.2; high-grade slip: SRS-24: 95.6 vs. 90.6, ODI: 3.4 vs. 6.9, VAS low-back pain: 10.5 vs. 22.1). The differences were statistically significant for ODI and VAS in high-grade patients in favor of the children. The clinical relevance of these differences seems to be minimal. The results of the comparison of the matched cohorts were comparably good. One-fifth of the whole study group had a non-union which did not affect the final outcome. In the children with high-grade slips, there was a mean slip improvement of 14 percentage points due to remodelling. The overall complication rate in the whole population was 7.7%. In conclusion, spinal fusion can be carried out at an early age for low- and high-grade spondylolisthesis with good long-term clinical, functional, radiographic and health-related quality-of-life outcomes when the indications are met. Springer-Verlag, 2010 Spondylolisthesis nationallicence Surgery nationallicence Children nationallicence Adolescents nationallicence Comparative study nationallicence Jalanko Tuomas ORTON Orthopaedic Hospital, Invalid Foundation, Tenholantie 10, 00280, Helsinki, Finland aut Helenius Ilkka Turku Children's Hospital, Turku University Central Hospital, Kiinamyllynkatu 4-8, 20521, Turku, Finland aut Remes Ville Peijas Hospital, Helsinki University Central Hospital, P.O. Box 900, 00029 HUS, Helsinki, Finland aut Lamberg Tommi Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Topeliuksenkatu 5, P.O. Box 266, 00029 HUS, Helsinki, Finland aut Tervahartiala Pekka HUS-Röntgen, Helsinki University Central Hospital, Tukholmankatu 2, P.O. Box 750, 00029 HUS, Helsinki, Finland aut Yrjönen Timo ORTON Orthopaedic Hospital, Invalid Foundation, Tenholantie 10, 00280, Helsinki, Finland aut Poussa Mikko ORTON Orthopaedic Hospital, Invalid Foundation, Tenholantie 10, 00280, Helsinki, Finland aut Schlenzka Dietrich ORTON Orthopaedic Hospital, Invalid Foundation, Tenholantie 10, 00280, Helsinki, Finland aut European Spine Journal Springer-Verlag 20/5(2011-05-01), 766-775 0940-6719 20:5<766 2011 20 586 https://doi.org/10.1007/s00586-010-1591-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-010-1591-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jalanko Tuomas ORTON Orthopaedic Hospital, Invalid Foundation, Tenholantie 10, 00280, Helsinki, Finland aut NATIONALLICENCE 700 1- Helenius Ilkka Turku Children's Hospital, Turku University Central Hospital, Kiinamyllynkatu 4-8, 20521, Turku, Finland aut NATIONALLICENCE 700 1- Remes Ville Peijas Hospital, Helsinki University Central Hospital, P.O. Box 900, 00029 HUS, Helsinki, Finland aut NATIONALLICENCE 700 1- Lamberg Tommi Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Topeliuksenkatu 5, P.O. Box 266, 00029 HUS, Helsinki, Finland aut NATIONALLICENCE 700 1- Tervahartiala Pekka HUS-Röntgen, Helsinki University Central Hospital, Tukholmankatu 2, P.O. Box 750, 00029 HUS, Helsinki, Finland aut NATIONALLICENCE 700 1- Yrjönen Timo ORTON Orthopaedic Hospital, Invalid Foundation, Tenholantie 10, 00280, Helsinki, Finland aut NATIONALLICENCE 700 1- Poussa Mikko ORTON Orthopaedic Hospital, Invalid Foundation, Tenholantie 10, 00280, Helsinki, Finland aut NATIONALLICENCE 700 1- Schlenzka Dietrich ORTON Orthopaedic Hospital, Invalid Foundation, Tenholantie 10, 00280, Helsinki, Finland aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/5(2011-05-01), 766-775 0940-6719 20:5<766 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer