caa a22 4500 445834439 CHVBK 20180317145326.0 cr unu---uuuuu 170323e20110501xx s 000 0 eng 10.1007/s00586-010-1519-2 doi (NATIONALLICENCE)springer-10.1007/s00586-010-1519-2 Confirmation of microevolutionary increase in spina bifida occulta among Swiss birth cohorts [Elektronische Daten] [Yu Lee, Lucian Solomon, Frank Rühli, Regula Schiess, Lena Öhrström, Thomas Sullivan, Hatem Alkadhi, Maciej Henneberg] Previous studies on the prevalence of spina bifida occulta have indicated a microevolutionary increase in its frequency and possible population differences in the prevalence of the condition. We studied the frequencies of closed and open sacral canals at each sacral level among two birth cohorts in Switzerland. Transverse CT scans and multiplanar reconstruction images of sacra of 95 males and 96 females born in 1940-1950 and 99 males and 94 females born in 1970-1980 in Switzerland were reviewed. We found that individuals born later have significantly more open sacral arches at all sacral levels compared to those born 30-40years earlier. When results were related to previously published data on Australian cohorts, the trend was the same, but Swiss in both cohorts were less likely to have an open section than Australians at all locations apart from S2. This study confirmed a microevolutionary trend in the opening of sacral canal among two different generations in Switzerland and demonstrated a population difference in the prevalence of spina bifida occulta. Springer-Verlag, 2010 Sacrum nationallicence Opened sacral arches nationallicence Secular trend nationallicence Anatomical variation nationallicence Lee Yu Department of Orthopaedics and Trauma, Royal Adelaide Hospital, Level 4 Bice Building, RAH, 5000, North Terrace, Adelaide, SA, Australia aut Solomon Lucian Department of Orthopaedics and Trauma, Royal Adelaide Hospital, Level 4 Bice Building, RAH, 5000, North Terrace, Adelaide, SA, Australia aut Rühli Frank Institute of Anatomy, University of Zürich, Winterthurerstr. 190, 8057, Zürich, Switzerland aut Schiess Regula Institute of Anatomy, University of Zürich, Winterthurerstr. 190, 8057, Zürich, Switzerland aut Öhrström Lena Institute of Anatomy, University of Zürich, Winterthurerstr. 190, 8057, Zürich, Switzerland aut Sullivan Thomas Discipline of Public Health, The University of Adelaide, 5005, North Terrace, SA, Australia aut Alkadhi Hatem Institute of Diagnostic Radiology, University Hospital Zurich, Zürich, Switzerland aut Henneberg Maciej Biological Anthropology and Comparative Anatomy Research Unit, The University of Adelaide, 5005, North Terrace, SA, Australia aut European Spine Journal Springer-Verlag 20/5(2011-05-01), 776-780 0940-6719 20:5<776 2011 20 586 https://doi.org/10.1007/s00586-010-1519-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00586-010-1519-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lee Yu Department of Orthopaedics and Trauma, Royal Adelaide Hospital, Level 4 Bice Building, RAH, 5000, North Terrace, Adelaide, SA, Australia aut NATIONALLICENCE 700 1- Solomon Lucian Department of Orthopaedics and Trauma, Royal Adelaide Hospital, Level 4 Bice Building, RAH, 5000, North Terrace, Adelaide, SA, Australia aut NATIONALLICENCE 700 1- Rühli Frank Institute of Anatomy, University of Zürich, Winterthurerstr. 190, 8057, Zürich, Switzerland aut NATIONALLICENCE 700 1- Schiess Regula Institute of Anatomy, University of Zürich, Winterthurerstr. 190, 8057, Zürich, Switzerland aut NATIONALLICENCE 700 1- Öhrström Lena Institute of Anatomy, University of Zürich, Winterthurerstr. 190, 8057, Zürich, Switzerland aut NATIONALLICENCE 700 1- Sullivan Thomas Discipline of Public Health, The University of Adelaide, 5005, North Terrace, SA, Australia aut NATIONALLICENCE 700 1- Alkadhi Hatem Institute of Diagnostic Radiology, University Hospital Zurich, Zürich, Switzerland aut NATIONALLICENCE 700 1- Henneberg Maciej Biological Anthropology and Comparative Anatomy Research Unit, The University of Adelaide, 5005, North Terrace, SA, Australia aut NATIONALLICENCE 773 0- European Spine Journal Springer-Verlag 20/5(2011-05-01), 776-780 0940-6719 20:5<776 2011 20 586 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer