caa a22 4500 445840234 CHVBK 20180317145341.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s00709-010-0225-6 doi (NATIONALLICENCE)springer-10.1007/s00709-010-0225-6 Cell-to-cell trafficking of RNA and RNA silencing through plasmodesmata [Elektronische Daten] [Tae Hyun, Mohammad Uddin, Yeonggil Rim, Jae-Yean Kim] Plasmodesmata (PD) are plasma membrane-lined cytoplasmic channels that cross the cell wall and establish symplasmic continuity between neighboring cells in plants. Recently, a wide range of cellular RNAs (including mRNAs and small RNAs (sRNAs)) have been reported to move from cell to cell through PD trafficking pathways. sRNAs are key molecules that function in transcriptional and post-transcriptional RNA silencing, which is a gene expression regulatory mechanism that is conserved among eukaryotes and is important for protection against invading nucleic acids (such as viruses and transposons) and for developmental and physiological regulation. One of the most intriguing aspects of RNA silencing is that it can function either cell autonomously or non-cell autonomously in post-transcriptional RNA silencing pathways. Although the mechanisms underlying cell-to-cell trafficking of RNA and RNA silencing signals are not fully understood, the movement of specific RNAs seems to play a critical role in cell-to-cell and long-distance regulation of gene expression, thereby coordinating growth and developmental processes, gene silencing, and stress responses. In this review, we summarize the current knowledge regarding cell-to-cell trafficking of RNA molecules (including small RNAs), and we discuss potential molecular mechanisms of cell-to-cell trafficking that are mediated by complex networks. Springer-Verlag, 2010 Movement protein nationallicence Non-cell autonomous nationallicence Plasmodesmata nationallicence Spread of RNA silencing nationallicence RNA trafficking nationallicence Small RNA nationallicence miRNA : MicroRNA nationallicence MP : Movement protein nationallicence NCAP : Non-cell-autonomous protein nationallicence PD : Plasmodesmata nationallicence SEL : Size exclusion limit nationallicence siRNA : Short interfering RNA nationallicence sRNA : Small RNA nationallicence Hyun Tae Department of Biochemistry, Division of Applied Life Science (BK21 program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 660-701, Jinju, South Korea aut Uddin Mohammad Department of Biochemistry, Division of Applied Life Science (BK21 program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 660-701, Jinju, South Korea aut Rim Yeonggil Department of Biochemistry, Division of Applied Life Science (BK21 program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 660-701, Jinju, South Korea aut Kim Jae-Yean Department of Biochemistry, Division of Applied Life Science (BK21 program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 660-701, Jinju, South Korea aut Protoplasma Springer Vienna 248/1(2011-01-01), 101-116 0033-183X 248:1<101 2011 248 709 https://doi.org/10.1007/s00709-010-0225-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00709-010-0225-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hyun Tae Department of Biochemistry, Division of Applied Life Science (BK21 program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 660-701, Jinju, South Korea aut NATIONALLICENCE 700 1- Uddin Mohammad Department of Biochemistry, Division of Applied Life Science (BK21 program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 660-701, Jinju, South Korea aut NATIONALLICENCE 700 1- Rim Yeonggil Department of Biochemistry, Division of Applied Life Science (BK21 program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 660-701, Jinju, South Korea aut NATIONALLICENCE 700 1- Kim Jae-Yean Department of Biochemistry, Division of Applied Life Science (BK21 program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, 660-701, Jinju, South Korea aut NATIONALLICENCE 773 0- Protoplasma Springer Vienna 248/1(2011-01-01), 101-116 0033-183X 248:1<101 2011 248 709 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer