caa a22 4500 445840609 CHVBK 20180317145342.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00709-010-0250-5 doi (NATIONALLICENCE)springer-10.1007/s00709-010-0250-5 McFadden Geoffrey School of Botany, University of Melbourne, 3010, Melbourne, VIC, Australia aut The apicoplast [Elektronische Daten] [Geoffrey McFadden] Parasites like malaria and Toxoplasma possess a vestigial plastid homologous to the chloroplasts of plants. The plastid (known as the apicoplast) is non-photosynthetic but retains many hallmarks of its ancestry including a circular genome that it synthesises proteins from and a suite of biosynthetic pathways of cyanobacterial origin. In this review, the discovery of the apicoplast and its integration, function and purpose are explored. New insights into the apicoplast fatty acid biosynthesis pathway and some novel roles of the apicoplast in vaccine development are reviewed. Springer-Verlag, 2010 Apicoplast nationallicence Endosymbiosis nationallicence Malaria nationallicence Plasmodium nationallicence Plastid nationallicence Toxoplasma nationallicence ER : Endoplasmic reticulum nationallicence ERAD : Endoplasmic reticulum-associated protein degradation nationallicence pPTs : Plastidic phosphate translocators nationallicence SELMA : Symbiont-specific ERAD-like machinery nationallicence Protoplasma Springer Vienna 248/4(2011-10-01), 641-650 0033-183X 248:4<641 2011 248 709 https://doi.org/10.1007/s00709-010-0250-5 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00709-010-0250-5 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- McFadden Geoffrey School of Botany, University of Melbourne, 3010, Melbourne, VIC, Australia aut NATIONALLICENCE 773 0- Protoplasma Springer Vienna 248/4(2011-10-01), 641-650 0033-183X 248:4<641 2011 248 709 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer