caa a22 4500 445840641 CHVBK 20180317145343.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s00709-010-0219-4 doi (NATIONALLICENCE)springer-10.1007/s00709-010-0219-4 Özbek Suat Institute of Zoology, Department of Molecular Evolution and Genomics, University of Heidelberg, Im Neuenheimer Feld 230, 69120, Heidelberg, Germany aut The cnidarian nematocyst: a miniature extracellular matrix within a secretory vesicle [Elektronische Daten] [Suat Özbek] Nematocysts are the taxon-defining features of all cnidarians including jellyfish, sea anemones, and corals. They are highly sophisticated organelles used for the capture of prey and defense. The nematocyst capsule is produced within a giant post-Golgi vesicle, which is continuously fed by proteins from the secretory pathway. Mature nematocysts consist of a hollow capsule body in which a long tubule is coiled up that, upon discharge, is expelled in a harpoon-like fashion. This is accompanied by the release of a toxin cocktail stored in the capsule matrix. Nematocyst discharge, which is one of the fastest processes in biology, is driven by an extreme osmotic pressure of about 150bar. The molecular analysis of the nematocyst has from the beginning indicated a collagenous nature of the capsule structure. In particular, a large family of unusual minicollagens has been demonstrated to form the highly resistant scaffold of the capsule. Recent findings on the molecular composition of Hydra nematocysts have confirmed the notion of a specialized extracellular matrix, which is assembled during an intracellular secretion process to form the most complex predatory apparatus at the cellular level. Springer-Verlag, 2010 Cnidarians nationallicence Nematocyst nationallicence Organelle evolution nationallicence Extracellular matrix nationallicence ECM : extracellular matrix nationallicence TGN : trans-Golgi network nationallicence PG : proteoglycan nationallicence GAG : glycosaminoglycan nationallicence PNN : perineuronal net nationallicence CRD : cysteine-rich domain nationallicence NOWA : nematocyst outer wall antigen nationallicence SCP : sperm coating protein nationallicence CTLD : C-type lectin domain nationallicence Protoplasma Springer Vienna 248/4(2011-10-01), 635-640 0033-183X 248:4<635 2011 248 709 https://doi.org/10.1007/s00709-010-0219-4 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00709-010-0219-4 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Özbek Suat Institute of Zoology, Department of Molecular Evolution and Genomics, University of Heidelberg, Im Neuenheimer Feld 230, 69120, Heidelberg, Germany aut NATIONALLICENCE 773 0- Protoplasma Springer Vienna 248/4(2011-10-01), 635-640 0033-183X 248:4<635 2011 248 709 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer