caa a22 4500 445842407 CHVBK 20180317145348.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s11047-010-9237-6 doi (NATIONALLICENCE)springer-10.1007/s11047-010-9237-6 A renewable, modular, and time-responsive DNA circuit [Elektronische Daten] [Ashish Goel, Morteza Ibrahimi] In this article, we introduce a new design for DNA logic gates based on enzymatic restriction of DNA strands. We present a construction for a set of one and two-input logic gates and argue that our construction can be generalized to implement any Boolean operation. A key feature of our design is its time-responsiveness, in the presence of appropriate fuels our circuit can operate continuously and generate a time-dependent output in response to a time-dependent input. Moreover, modulo connectivity information, the strand design and circuit design phases are decoupled. Springer Science+Business Media B.V., 2010 DNA nanotechnology nationallicence Logic gates nationallicence DNA circuit nationallicence Time-responsive circuit nationallicence Digital circuit nationallicence Goel Ashish Departments of Management Science and Engineering and (by courtesy) Computer Science, Stanford University, Stanford, CA, USA aut Ibrahimi Morteza Departments of Electrical Engineering, Stanford University, Stanford, CA, USA aut Natural Computing Springer Netherlands 10/1(2011-03-01), 467-485 1567-7818 10:1<467 2011 10 11047 https://doi.org/10.1007/s11047-010-9237-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11047-010-9237-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Goel Ashish Departments of Management Science and Engineering and (by courtesy) Computer Science, Stanford University, Stanford, CA, USA aut NATIONALLICENCE 700 1- Ibrahimi Morteza Departments of Electrical Engineering, Stanford University, Stanford, CA, USA aut NATIONALLICENCE 773 0- Natural Computing Springer Netherlands 10/1(2011-03-01), 467-485 1567-7818 10:1<467 2011 10 11047 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer