caa a22 4500 445844760 CHVBK 20180317145355.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s10709-010-9483-7 doi (NATIONALLICENCE)springer-10.1007/s10709-010-9483-7 Safe and fit genetically modified insects for pest control: from lab to field applications [Elektronische Daten] [F. Scolari, P. Siciliano, P. Gabrieli, L. Gomulski, A. Bonomi, G. Gasperi, A. Malacrida] Insect transgenesis is continuously being improved to increase the efficacy of population suppression and replacement strategies directed to the control of insect species of economic and sanitary interest. An essential prerequisite for the success of both pest control applications is that the fitness of the transformant individuals is not impaired, so that, once released in the field, they can efficiently compete with or even out-compete their wild-type counterparts for matings in order to reduce the population size, or to spread desirable genes into the target population. Recent research has shown that the production of fit and competitive transformants can now be achieved and that transgenes may not necessarily confer a fitness cost. In this article we review the most recent published results of the fitness assessment of different transgenic insect lines and underline the necessity to fulfill key requirements of ecological safety. Fitness evaluation studies performed in field cages and medium/large-scale rearing will validate the present encouraging laboratory results, giving an indication of the performance of the transgenic insect genotype after release in pest control programmes. Springer Science+Business Media B.V., 2010 Fitness nationallicence Transgenesis nationallicence SIT nationallicence Population replacement nationallicence Scolari F. Department of Animal Biology, University of Pavia, Pavia, Italy aut Siciliano P. Department of Animal Biology, University of Pavia, Pavia, Italy aut Gabrieli P. Department of Animal Biology, University of Pavia, Pavia, Italy aut Gomulski L. Department of Animal Biology, University of Pavia, Pavia, Italy aut Bonomi A. Department of Animal Biology, University of Pavia, Pavia, Italy aut Gasperi G. Department of Animal Biology, University of Pavia, Pavia, Italy aut Malacrida A. Department of Animal Biology, University of Pavia, Pavia, Italy aut Genetica Springer Netherlands 139/1(2011-01-01), 41-52 0016-6707 139:1<41 2011 139 10709 https://doi.org/10.1007/s10709-010-9483-7 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10709-010-9483-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Scolari F. Department of Animal Biology, University of Pavia, Pavia, Italy aut NATIONALLICENCE 700 1- Siciliano P. Department of Animal Biology, University of Pavia, Pavia, Italy aut NATIONALLICENCE 700 1- Gabrieli P. Department of Animal Biology, University of Pavia, Pavia, Italy aut NATIONALLICENCE 700 1- Gomulski L. Department of Animal Biology, University of Pavia, Pavia, Italy aut NATIONALLICENCE 700 1- Bonomi A. Department of Animal Biology, University of Pavia, Pavia, Italy aut NATIONALLICENCE 700 1- Gasperi G. Department of Animal Biology, University of Pavia, Pavia, Italy aut NATIONALLICENCE 700 1- Malacrida A. Department of Animal Biology, University of Pavia, Pavia, Italy aut NATIONALLICENCE 773 0- Genetica Springer Netherlands 139/1(2011-01-01), 41-52 0016-6707 139:1<41 2011 139 10709 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer