caa a22 4500 445845031 CHVBK 20180317145356.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s10709-011-9613-x doi (NATIONALLICENCE)springer-10.1007/s10709-011-9613-x Molecular characterization of a genomic interval with highly uneven recombination distribution on maize chromosome 10 L [Elektronische Daten] [Gang Wang, Jianping Xu, Yuanping Tang, Liangliang Zhou, Fei Wang, Zhengkai Xu, Rentao Song] Homologous recombination in meiosis provides the evolutionary driving force in eukaryotic organisms by generating genetic variability. Meiotic recombination does not always occur evenly across the chromosome, and therefore genetic and physical distances are not consistently in proportion. We discovered a 278kb interval on the long arm of chromosome 10 (10 L) through analyzed 13,933 descendants of backcross population. The recombinant events distributed unevenly in the interval. The ratio of genetic to physical distance in the interval fluctuated about 47-fold. With the assistance of molecular markers, the interval was divided into several subintervals for further characterization. In agreement with previous observations, high gene-density regions such as subinterval A and B were also genetic recombination hot subintervals, and repetitive sequence-riched region such as subinterval C was also found to be recombination inert at the detection level of the study. However, we found an unusual subinterval D, in which the 72-kb region contained 6 genes. The gene-density of subinterval D was 5.8 times that of the genome-wide average. The ratio of genetic to physical distance in subinterval D was 0.58cM/Mb, only about 3/4 of the genome average. We carried out an analysis of sequence polymorphisms and methylation status in subinterval D, and the potential causes of recombination suppression were discussed. This study was another case of a detailed genetic analysis of an unusual recombination region in the maize genome. Springer Science+Business Media B.V., 2011 Maize nationallicence Recombination nationallicence Sequence polymorphism nationallicence Methylation nationallicence Wang Gang Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut Xu Jianping Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut Tang Yuanping Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut Zhou Liangliang Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut Wang Fei Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut Xu Zhengkai Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut Song Rentao Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut Genetica Springer Netherlands 139/9(2011-09-01), 1109-1118 0016-6707 139:9<1109 2011 139 10709 https://doi.org/10.1007/s10709-011-9613-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10709-011-9613-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Gang Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Xu Jianping Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Tang Yuanping Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Zhou Liangliang Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Wang Fei Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Xu Zhengkai Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut NATIONALLICENCE 700 1- Song Rentao Shanghai Key Laboratory of Bio-Energy Crop, School of Life Sciences, Shanghai University, 99 Shangda Road, 200444, Shanghai, People's Republic of China aut NATIONALLICENCE 773 0- Genetica Springer Netherlands 139/9(2011-09-01), 1109-1118 0016-6707 139:9<1109 2011 139 10709 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer