caa a22 4500 44584504X CHVBK 20180317145356.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s10709-011-9619-4 doi (NATIONALLICENCE)springer-10.1007/s10709-011-9619-4 Genetic diversity of Ovis aries populations near domestication centers and in the New World [Elektronische Daten] [H. Blackburn, Y. Toishibekov, M. Toishibekov, C. Welsh, S. Spiller, M. Brown, S. Paiva] Domestic sheep in Kazakhstan may provide an interesting source of genetic variability due to their proximity to the center of domestication and the Silk Route. Additionally, those breeds have never been compared to New World sheep populations. This report compares genetic diversity among five Kazakhstan (KZ) and 13 United States (US) sheep breeds (N=442) using 25 microsatellite markers from the FAO panel. The KZ breeds had observed and expected measures of heterozygosity greater than 0.60 and an average number of alleles per locus of 7.8. In contrast, US sheep breeds had observed heterozygosity ranged from 0.37 to 0.62 and had an average number of alleles of 5.7. A Bayesian analysis indicated there were two primary populations (K=2). Surprisingly, the US breeds were near evenly split between the two clusters, while all of the KZ breeds were placed in one of the two clusters. Pooling breeds within country of sample origin showed KZ and US populations to have similar levels of expected heterozygosity and the average number of alleles per locus. The results of breeds pooled within country suggest that there was no difference between countries for these diversity measures using this set of neutral markers. This finding suggests that populations' geographically isolated from centers of domestication can be more diverse than previously thought, and as a result, conservation strategies can be adjusted accordingly. Furthermore, these results suggest there may be limited need for countries to alter the protocols for trade and exchange of animal genetic resources that are in place today, since no one population has a unique set of private alleles. Springer Science+Business Media B.V. (outside the USA), 2011 Genetic diversity nationallicence Sheep nationallicence Conservation of genetic resources nationallicence Kazakhstan nationallicence Blackburn H. National Center for Genetic Resources Preservation, National Animal Germplasm Program, USDA-ARS, Ft. Collins, CO, USA aut Toishibekov Y. Institute of Experimental Biology, Almaty, KZ, USA aut Toishibekov M. Institute of Experimental Biology, Almaty, KZ, USA aut Welsh C. National Center for Genetic Resources Preservation, National Animal Germplasm Program, USDA-ARS, Ft. Collins, CO, USA aut Spiller S. National Center for Genetic Resources Preservation, National Animal Germplasm Program, USDA-ARS, Ft. Collins, CO, USA aut Brown M. Grazing Lands Research Laboratory, USDA-ARS, El Reno, OK, USA aut Paiva S. EMBRAPA Recursos Genéticos e Biotecnologia (EMBRAPA Genetic Resources and Biotechnology - CENARGEN, Brasillia, DF, USA aut Genetica Springer Netherlands 139/9(2011-09-01), 1169-1178 0016-6707 139:9<1169 2011 139 10709 https://doi.org/10.1007/s10709-011-9619-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10709-011-9619-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Blackburn H. National Center for Genetic Resources Preservation, National Animal Germplasm Program, USDA-ARS, Ft. Collins, CO, USA aut NATIONALLICENCE 700 1- Toishibekov Y. Institute of Experimental Biology, Almaty, KZ, USA aut NATIONALLICENCE 700 1- Toishibekov M. Institute of Experimental Biology, Almaty, KZ, USA aut NATIONALLICENCE 700 1- Welsh C. National Center for Genetic Resources Preservation, National Animal Germplasm Program, USDA-ARS, Ft. Collins, CO, USA aut NATIONALLICENCE 700 1- Spiller S. National Center for Genetic Resources Preservation, National Animal Germplasm Program, USDA-ARS, Ft. Collins, CO, USA aut NATIONALLICENCE 700 1- Brown M. Grazing Lands Research Laboratory, USDA-ARS, El Reno, OK, USA aut NATIONALLICENCE 700 1- Paiva S. EMBRAPA Recursos Genéticos e Biotecnologia (EMBRAPA Genetic Resources and Biotechnology - CENARGEN, Brasillia, DF, USA aut NATIONALLICENCE 773 0- Genetica Springer Netherlands 139/9(2011-09-01), 1169-1178 0016-6707 139:9<1169 2011 139 10709 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer