caa a22 4500 445845325 CHVBK 20180317145357.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10709-012-9634-0 doi (NATIONALLICENCE)springer-10.1007/s10709-012-9634-0 Interspecies linkage analysis of mo, a Bombyx mori locus associated with mosaicism and gynandromorphism [Elektronische Daten] [T. Fujii, H. Abe, K. Yamamoto, S. Katsuma, T. Shimada] The mo (hereditary mosaic) mutation is one of the most famous and interesting mutations of the silkworm, Bombyx mori. Females homozygous for mo generate mosaic and gynandromorphic offspring due to non-elimination of polar bodies and subsequent double fertilization events, irrespective of the genotype of the mated males. Although mo was first reported in 1927, the locus has not been mapped to linkage groups, as the mutation is unstable and appears to be sensitive to genetic background. In this study, linkage analysis of mo was performed using PCR-based markers on single nucleotide polymorphism linkage maps. Bombyx mandarina was used as the mating partner for the B. mori mo strain, as it is easier to identify polymorphic markers between B. mori and B. mandarina than within B. mori strains. Surprisingly, we identified two homozygous linkage groups (LGs) in all of the 12 B1 (first backcross generation) moths that had deposited mosaic eggs. It was revealed that + mo is located on the M chromosome of B. mandarina, which corresponds to two linkage groups of B. mori, LG 14 and 27. Based on further linkage analysis using B. mori as a mating partner, mo was mapped to LG 14. Additionally, we found that mo activity could be modified by a gene(s) on LG 17. Springer Science+Business Media B.V., 2012 Mosaic nationallicence Gynandromorph nationallicence Bombyx mori nationallicence Bombyx mandarina nationallicence Linkage mapping nationallicence Single nucleotide polymorphism (SNP) nationallicence Fujii T. Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, 113-8657, Bunkyo-ku, Tokyo, Japan aut Abe H. Department of Biological Production, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Saiwai-cho 3-5-8, 183-8509, Fuchu, Tokyo, Japan aut Yamamoto K. National Institute of Agrobiological Sciences, Owashi 1-2, 305-8634, Tsukuba, Ibaraki, Japan aut Katsuma S. Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, 113-8657, Bunkyo-ku, Tokyo, Japan aut Shimada T. Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, 113-8657, Bunkyo-ku, Tokyo, Japan aut Genetica Springer Netherlands 139/10(2011-10-01), 1323-1329 0016-6707 139:10<1323 2011 139 10709 https://doi.org/10.1007/s10709-012-9634-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10709-012-9634-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fujii T. Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, 113-8657, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Abe H. Department of Biological Production, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Saiwai-cho 3-5-8, 183-8509, Fuchu, Tokyo, Japan aut NATIONALLICENCE 700 1- Yamamoto K. National Institute of Agrobiological Sciences, Owashi 1-2, 305-8634, Tsukuba, Ibaraki, Japan aut NATIONALLICENCE 700 1- Katsuma S. Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, 113-8657, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Shimada T. Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, 113-8657, Bunkyo-ku, Tokyo, Japan aut NATIONALLICENCE 773 0- Genetica Springer Netherlands 139/10(2011-10-01), 1323-1329 0016-6707 139:10<1323 2011 139 10709 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer