caa a22 4500 445845406 CHVBK 20180317145357.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10709-011-9566-0 doi (NATIONALLICENCE)springer-10.1007/s10709-011-9566-0 Population transcriptomics: insights from Drosophila simulans, Drosophila sechellia and their hybrids [Elektronische Daten] [François Wurmser, David Ogereau, Tristan Mary-Huard, Béatrice Loriod, Dominique Joly, Catherine Montchamp-Moreau] Sequence differentiation has been widely studied between populations and species, whereas interest in expression divergence is relatively recent. Using microarrays, we compared four geographically distinct populations of Drosophila simulans and a population of Drosophila sechellia, and interspecific hybrids. We observed few differences between populations, suggesting a slight population structure in D. simulans. This structure was observed in direct population comparisons, as well as in interspecific comparisons (hybrids vs. parents, D. sechellia vs. D. simulans). Expression variance is higher in the French and Zimbabwean populations than in the populations from the ancestral range of D. simulans (Kenya and Seychelles). This suggests a large scale phenomenon of decanalization following the invasion of a new environment. Comparing D. simulans and D. sechellia, we revealed 304 consistently differentially expressed genes, with striking overrepresentation of genes of the cytochrome P450 family, which could be related to their role in detoxification as well as in hormone regulation. We also revealed differences in genes involved in Juvenile hormone and Dopamine differentiation. We finally observed very few differentially expressed genes between hybrids and parental populations, with an overrepresentation of X-linked genes. Springer Science+Business Media B.V., 2011 Expression differentiation nationallicence Population structure nationallicence Ecology nationallicence CYP450 nationallicence Hormone regulation nationallicence Drosophila nationallicence Wurmser François Laboratoire Evolution, Génomes et Spéciation, CNRS UPR9034 Avenue de la Terrasse, Gif-sur-Yvette F-91198 Cedex, and Univ Paris-Sud, 91405, Orsay, France aut Ogereau David Laboratoire Evolution, Génomes et Spéciation, CNRS UPR9034 Avenue de la Terrasse, Gif-sur-Yvette F-91198 Cedex, and Univ Paris-Sud, 91405, Orsay, France aut Mary-Huard Tristan Statistics and Genomes Team, INRA UMR518/AgroParisTech, 16 rue Claude Bernard, 75231, Paris, France aut Loriod Béatrice U928 INSERM, Parc scientifique de Luminy, 163 Avenue de Luminy, case 928, 13288, Marseille Cedex 09, France aut Joly Dominique Laboratoire Evolution, Génomes et Spéciation, CNRS UPR9034 Avenue de la Terrasse, Gif-sur-Yvette F-91198 Cedex, and Univ Paris-Sud, 91405, Orsay, France aut Montchamp-Moreau Catherine Laboratoire Evolution, Génomes et Spéciation, CNRS UPR9034 Avenue de la Terrasse, Gif-sur-Yvette F-91198 Cedex, and Univ Paris-Sud, 91405, Orsay, France aut Genetica Springer Netherlands 139/4(2011-04-01), 465-477 0016-6707 139:4<465 2011 139 10709 https://doi.org/10.1007/s10709-011-9566-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10709-011-9566-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wurmser François Laboratoire Evolution, Génomes et Spéciation, CNRS UPR9034 Avenue de la Terrasse, Gif-sur-Yvette F-91198 Cedex, and Univ Paris-Sud, 91405, Orsay, France aut NATIONALLICENCE 700 1- Ogereau David Laboratoire Evolution, Génomes et Spéciation, CNRS UPR9034 Avenue de la Terrasse, Gif-sur-Yvette F-91198 Cedex, and Univ Paris-Sud, 91405, Orsay, France aut NATIONALLICENCE 700 1- Mary-Huard Tristan Statistics and Genomes Team, INRA UMR518/AgroParisTech, 16 rue Claude Bernard, 75231, Paris, France aut NATIONALLICENCE 700 1- Loriod Béatrice U928 INSERM, Parc scientifique de Luminy, 163 Avenue de Luminy, case 928, 13288, Marseille Cedex 09, France aut NATIONALLICENCE 700 1- Joly Dominique Laboratoire Evolution, Génomes et Spéciation, CNRS UPR9034 Avenue de la Terrasse, Gif-sur-Yvette F-91198 Cedex, and Univ Paris-Sud, 91405, Orsay, France aut NATIONALLICENCE 700 1- Montchamp-Moreau Catherine Laboratoire Evolution, Génomes et Spéciation, CNRS UPR9034 Avenue de la Terrasse, Gif-sur-Yvette F-91198 Cedex, and Univ Paris-Sud, 91405, Orsay, France aut NATIONALLICENCE 773 0- Genetica Springer Netherlands 139/4(2011-04-01), 465-477 0016-6707 139:4<465 2011 139 10709 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer