caa a22 4500 445845430 CHVBK 20180317145357.0 cr unu---uuuuu 170323e20110401xx s 000 0 eng 10.1007/s10709-011-9563-3 doi (NATIONALLICENCE)springer-10.1007/s10709-011-9563-3 Slow inbred lines of Drosophila melanogaster express as much inbreeding depression as fast inbred lines under semi-natural conditions [Elektronische Daten] [Torsten Kristensen, Morten Knudsen, Volker Loeschcke] Selection may reduce the deleterious consequences of inbreeding. This may be due to purging of recessive deleterious alleles or balancing selection favouring heterozygote offspring. Such selection is expected to be more efficient at slower compared to at faster rates of inbreeding. In this study we tested the impact of inbreeding and the rate of inbreeding on fitness related traits (egg productivity, egg-to-adult viability, developmental time and behaviour) under cold and benign semi-natural thermal conditions using Drosophila melanogaster as a model organism. We used non-inbred control and slow and fast inbred lines (both with an expected inbreeding level of 0.25). The results show that contrary to expectations the slow inbred lines do not maintain higher average fitness than the fast inbred lines. Furthermore, we found that stressful environmental conditions increased the level of inbreeding depression but the impact of inbreeding rate on the level of inbreeding depression was not affected by the environmental conditions. The results do not support the hypothesis that inbreeding depression is less severe with slow compared to fast rates of inbreeding and illustrate that although selection may be more efficient with slower rates of inbreeding this does not necessary lead to less inbreeding depression. Springer Science+Business Media B.V., 2011 Balancing selection nationallicence Environmental stress nationallicence Inbreeding rate nationallicence Purging nationallicence Heterozygosity nationallicence Kristensen Torsten Department of Genetics and Biotechnology, Aarhus University, Blichers Allé 20, 8830, Tjele, Denmark aut Knudsen Morten Genetics and Ecology, Department of Biological Sciences, Aarhus University, Ny Munkegade 114, Building 1540, 8000, Aarhus C, Denmark aut Loeschcke Volker Genetics and Ecology, Department of Biological Sciences, Aarhus University, Ny Munkegade 114, Building 1540, 8000, Aarhus C, Denmark aut Genetica Springer Netherlands 139/4(2011-04-01), 441-451 0016-6707 139:4<441 2011 139 10709 https://doi.org/10.1007/s10709-011-9563-3 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10709-011-9563-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kristensen Torsten Department of Genetics and Biotechnology, Aarhus University, Blichers Allé 20, 8830, Tjele, Denmark aut NATIONALLICENCE 700 1- Knudsen Morten Genetics and Ecology, Department of Biological Sciences, Aarhus University, Ny Munkegade 114, Building 1540, 8000, Aarhus C, Denmark aut NATIONALLICENCE 700 1- Loeschcke Volker Genetics and Ecology, Department of Biological Sciences, Aarhus University, Ny Munkegade 114, Building 1540, 8000, Aarhus C, Denmark aut NATIONALLICENCE 773 0- Genetica Springer Netherlands 139/4(2011-04-01), 441-451 0016-6707 139:4<441 2011 139 10709 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer