caa a22 4500 445847557 CHVBK 20180317145403.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10548-011-0176-z doi (NATIONALLICENCE)springer-10.1007/s10548-011-0176-z Neural Correlates of Familiar and Unfamiliar Face Processing in Infants at Risk for Autism Spectrum Disorders [Elektronische Daten] [Rhiannon Luyster, Jennifer Wagner, Vanessa Vogel-Farley, Helen Tager-Flusberg, Charles Nelson III] Examining the neural correlates associated with processing social stimuli offers a viable option to the challenge of studying early social processing in infants at risk for autism spectrum disorders (ASDs). The present investigation included 32 12-month olds at high risk for ASD and 24 low-risk control infants, defined on the basis of family history. Infants were presented with familiar and unfamiliar faces, and three components of interest were explored for amplitude and latency differences. The anticipated developmental effects of emerging hemispheric asymmetry for face-sensitive components (the N290 and P400) were observed, as were familiarity effects for a component related to attention (the Nc). Although there were no striking group differences in the neural response to faces, there was some evidence for a developmental lag in an attentional component for the high-risk group. The infant ASD endophenotype, though elusive, may be better defined through expanding the age of study and addressing change over time in response to varied stimuli. Springer Science+Business Media, LLC, 2011 Event related potentials nationallicence Infant nationallicence Autism spectrum disorders nationallicence Face processing nationallicence Luyster Rhiannon Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Children's Hospital Boston, 1 Autumn St., 6th Fl, 02215, Boston, MA, USA aut Wagner Jennifer Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Children's Hospital Boston, 1 Autumn St., 6th Fl, 02215, Boston, MA, USA aut Vogel-Farley Vanessa Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Children's Hospital Boston, 1 Autumn St., 6th Fl, 02215, Boston, MA, USA aut Tager-Flusberg Helen Department of Psychology, Boston University, 64 Cummington St., 02215, Boston, MA, USA aut Nelson III Charles Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Children's Hospital Boston, 1 Autumn St., 6th Fl, 02215, Boston, MA, USA aut Brain Topography Springer US; http://www.springer-ny.com 24/3-4(2011-10-01), 220-228 0896-0267 24:3-4<220 2011 24 10548 https://doi.org/10.1007/s10548-011-0176-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10548-011-0176-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Luyster Rhiannon Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Children's Hospital Boston, 1 Autumn St., 6th Fl, 02215, Boston, MA, USA aut NATIONALLICENCE 700 1- Wagner Jennifer Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Children's Hospital Boston, 1 Autumn St., 6th Fl, 02215, Boston, MA, USA aut NATIONALLICENCE 700 1- Vogel-Farley Vanessa Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Children's Hospital Boston, 1 Autumn St., 6th Fl, 02215, Boston, MA, USA aut NATIONALLICENCE 700 1- Tager-Flusberg Helen Department of Psychology, Boston University, 64 Cummington St., 02215, Boston, MA, USA aut NATIONALLICENCE 700 1- Nelson III Charles Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Children's Hospital Boston, 1 Autumn St., 6th Fl, 02215, Boston, MA, USA aut NATIONALLICENCE 773 0- Brain Topography Springer US; http://www.springer-ny.com 24/3-4(2011-10-01), 220-228 0896-0267 24:3-4<220 2011 24 10548 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer