caa a22 4500 445847581 CHVBK 20180317145403.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10548-011-0182-1 doi (NATIONALLICENCE)springer-10.1007/s10548-011-0182-1 Herdman Anthony School of Audiology and Speech Sciences, Faculty of Medicine, University of British Columbia, 2177 Wesbrook Mall, V6T 1Z3, Vancouver, BC, Canada aut Neuroimaging Evidence for Top-Down Maturation of Selective Auditory Attention [Elektronische Daten] [Anthony Herdman] This study investigated maturational differences of selective auditory attention effects on transient evoked responses and 40-Hz auditory steady-state responses between children and adults. Magnetoencephalography (MEG) was recorded from children and adults performing a task where they attended to 40-Hz amplitude-modulated (AM) tones of 1,200Hz while ignoring 40-Hz AM tones of 800Hz. By using standard dipole-modeling procedures, the N1m of the transient evoked fields and the 40-Hz ASSRs were localized to secondary and primary auditory cortices, respectively. Source waveforms for the transient evoked fields and ASSRs were reconstructed at these locations and compared between attended and unattended tones. Source waveforms revealed attention enhances the sustained negativity of the transient evoked responses in both adults and children around 250 and 400ms. ASSRs were also found to be enhanced within this time range but only for adults. The results provide evidence for a limited role of attention modification of the 40-Hz ASSRs in children around the age of 12years old. Because ASSRs are generated in a lower auditory processing stage as compared to the transient auditory evoked responses, findings from the present study could indicate that the maturation of attention progresses in top-to-bottom manner. These findings fit with the notion that as a person gains sensory experience selective gating of relevant from irrelevant information likely occurs at earlier and earlier processing levels in order to become more automatic and efficient. Springer Science+Business Media, LLC, 2011 Auditory evoked responses nationallicence Auditory steady-state responses nationallicence Magnetoencephalography nationallicence Development nationallicence Brain Topography Springer US; http://www.springer-ny.com 24/3-4(2011-10-01), 271-278 0896-0267 24:3-4<271 2011 24 10548 https://doi.org/10.1007/s10548-011-0182-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10548-011-0182-1 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Herdman Anthony School of Audiology and Speech Sciences, Faculty of Medicine, University of British Columbia, 2177 Wesbrook Mall, V6T 1Z3, Vancouver, BC, Canada aut NATIONALLICENCE 773 0- Brain Topography Springer US; http://www.springer-ny.com 24/3-4(2011-10-01), 271-278 0896-0267 24:3-4<271 2011 24 10548 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer