caa a22 4500 445847697 CHVBK 20180317145404.0 cr unu---uuuuu 170323e20111001xx s 000 0 eng 10.1007/s10548-011-0192-z doi (NATIONALLICENCE)springer-10.1007/s10548-011-0192-z The Development of Face Recognition; Hippocampal and Frontal Lobe Contributions Determined with MEG [Elektronische Daten] [Margot Taylor, Travis Mills, Elizabeth Pang] Face recognition skills improve steadily across childhood, yet few studies have investigated the development of the neural sources underlying these processes. We investigated the developmental changes in brain activity related specifically to face recognition, using magnetoencephalography (MEG). We studied 70 children (6-19years) and 20 young adults. Photographs of 240 neutral faces were used in two blocks of 1-back recognition tasks; one block contained faces upright and in the other block, faces were presented inverted. MEG activity was recorded on a 151 sensor CTF/MISL system. A structural MRI was acquired for all subjects. We focussed on the repetition effects of the faces, in a 280-680ms window, contrasting the repeated faces with the first presentation of the faces. The analyses showed reliable right hippocampal activation across all age groups, and a right inferior frontal activation that emerged for repeated, recognised faces at 10-11 years of age. The hippocampi are implicated in memory function and we demonstrate that the right hippocampus is specifically involved for face recognition. Further, we determined that this comes on-line by early school age, which is consistent with the known early maturation of the hippocampi. In contrast, we show that the right inferior frontal areas do not come on-line until later in childhood, consistent with the protracted development of the frontal cortices. These data support the hypothesis that different age groups use different strategies and neural structures for face recognition. Springer Science+Business Media, LLC, 2011 Recognition memory nationallicence Faces nationallicence MEG nationallicence Frontal lobes nationallicence Hippocampus nationallicence Taylor Margot Department of Diagnostic Imaging, Hospital for Sick Children, 555 University Ave, M5G 1X8, Toronto, ON, Canada aut Mills Travis Department of Diagnostic Imaging, Hospital for Sick Children, 555 University Ave, M5G 1X8, Toronto, ON, Canada aut Pang Elizabeth Division of Neurology, Hospital for Sick Children, Toronto, Canada aut Brain Topography Springer US; http://www.springer-ny.com 24/3-4(2011-10-01), 261-270 0896-0267 24:3-4<261 2011 24 10548 https://doi.org/10.1007/s10548-011-0192-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10548-011-0192-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Taylor Margot Department of Diagnostic Imaging, Hospital for Sick Children, 555 University Ave, M5G 1X8, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Mills Travis Department of Diagnostic Imaging, Hospital for Sick Children, 555 University Ave, M5G 1X8, Toronto, ON, Canada aut NATIONALLICENCE 700 1- Pang Elizabeth Division of Neurology, Hospital for Sick Children, Toronto, Canada aut NATIONALLICENCE 773 0- Brain Topography Springer US; http://www.springer-ny.com 24/3-4(2011-10-01), 261-270 0896-0267 24:3-4<261 2011 24 10548 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer