caa a22 4500 445847905 CHVBK 20180317145404.0 cr unu---uuuuu 170323e20110101xx s 000 0 eng 10.1007/s10548-010-0155-9 doi (NATIONALLICENCE)springer-10.1007/s10548-010-0155-9 Cortical Potential Imaging of Somatosensory Evoked Potentials by Means of the Boundary Element Method in Pediatric Epilepsy Patients [Elektronische Daten] [Xiaoxiao Bai, Vernon Towle, Wim van Drongelen, Bin He] The aim of the present study was to assess the feasibility of identifying the primary hand sensory area and central sulcus in pediatric patients using the cortical potential imaging (CPI) method from the scalp recorded somatosensory evoked potentials (SEPs). The CPI method was used to reconstruct the cortical potential distribution from the scalp potentials with the boundary element (3-layer: scalp, skull and brain) head model based on MR images of individual subjects. The cortical potentials estimated from the pre-operative scalp SEPs of four pediatric patients, were compared with the post-op subdural SEP recordings made in the same subjects. Estimated and directly recorded cortical SEP maps showed comparable spatial patterns on the cortical surface in four patients (spatial correlation coefficient >0.7 in the SEP spikes). For two of four patients, the estimated waveforms correlated significantly to the waveforms obtained by direct cortical recordings. The present results demonstrated the feasibility of the cortical potential imaging approach in noninvasive imaging spatial distribution and temporal waveforms of cortical potentials for pediatric patients. These also suggest that the CPI method may provide a promising means of estimating the cortical potential and noninvasive localizing the central sulcus to aid surgical planning for pediatric patients. Springer Science+Business Media, LLC, 2010 High-resolution EEG nationallicence Cortical potential imaging nationallicence SEP nationallicence Central sulcus nationallicence Cortical potential waveform nationallicence Bai Xiaoxiao Department of Biomedical Engineering, University of Minnesota, 7-105 NHH, 312 Church Street, 55455, Minneapolis, MN, USA aut Towle Vernon Department of Neurology, University of Chicago, Chicago, USA aut van Drongelen Wim Department of Neurology, University of Chicago, Chicago, USA aut He Bin Department of Biomedical Engineering, University of Minnesota, 7-105 NHH, 312 Church Street, 55455, Minneapolis, MN, USA aut Brain Topography Springer US; http://www.springer-ny.com 23/4(2011-01-01), 333-343 0896-0267 23:4<333 2011 23 10548 https://doi.org/10.1007/s10548-010-0155-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10548-010-0155-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bai Xiaoxiao Department of Biomedical Engineering, University of Minnesota, 7-105 NHH, 312 Church Street, 55455, Minneapolis, MN, USA aut NATIONALLICENCE 700 1- Towle Vernon Department of Neurology, University of Chicago, Chicago, USA aut NATIONALLICENCE 700 1- van Drongelen Wim Department of Neurology, University of Chicago, Chicago, USA aut NATIONALLICENCE 700 1- He Bin Department of Biomedical Engineering, University of Minnesota, 7-105 NHH, 312 Church Street, 55455, Minneapolis, MN, USA aut NATIONALLICENCE 773 0- Brain Topography Springer US; http://www.springer-ny.com 23/4(2011-01-01), 333-343 0896-0267 23:4<333 2011 23 10548 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer