caa a22 4500 445851112 CHVBK 20180317145413.0 cr unu---uuuuu 170323e20110301xx s 000 0 eng 10.1007/s10006-010-0225-x doi (NATIONALLICENCE)springer-10.1007/s10006-010-0225-x Oral submucous fibrosis: a clinicopathologic review of 205 cases in Indians [Elektronische Daten] [Punnya Angadi, K. Rekha] Introduction: Oral submucous fibrosis is a disease due to a chronic, insidious change in fibro-elasticity, characterized by burning sensation in the oral cavity, blanching, and stiffening of the oral mucosa and oro-pharynx leading to trismus and inability to open the mouth. The symptoms and signs depend on the progression of the lesions and number of affected sites. It is predominantly seen in Indians and other Asians. Once the disease has developed, there is neither regression nor any effective treatment. There are only few studies on the frequency and clinicopathological feature of oral submucous fibrosis in the Indian population in recent years. Material and methods: The present study evaluated 205 cases of oral submucous fibrosis for the age, sex, site of involvement, duration of disease at the time of diagnosis, associated habits and common presenting symptoms, presence of other mucosal lesions, malignant potential, and the histopathology. Results and discussion: Oral submucous fibrosis was seen in younger age (20-30 years) than that reported in literature and showed a characteristic male preponderance. A strong association with smokeless tobacco use especially arecanut in the form of gutkha was established and was related to earlier development of oral submucous fibrosis (OSMF), i.e., within a year of the habit. A total of 11.6% of cases were associated with malignancy and occurred predominantly in males. Conclusion: This article gives an insight into OSMF in this part of southern India and adds to its biologic profile. Springer-Verlag, 2010 Oral submucous fibrosis nationallicence Clinicopathologic features nationallicence Malignant potential nationallicence Areca nut nationallicence Smokeless tobacco nationallicence Angadi Punnya Department of Oral and Maxillofacial Pathology and Microbiology, KLE VK Institute of Dental Sciences, Nehru Nagar, 590010, Belgaum, India aut Rekha K. Department of Oral and Maxillofacial Pathology and Microbiology, SDM College of Dental Sciences, 580009, Dharwad, Karnataka, India aut Oral and Maxillofacial Surgery Springer-Verlag 15/1(2011-03-01), 15-19 1865-1550 15:1<15 2011 15 10006 https://doi.org/10.1007/s10006-010-0225-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10006-010-0225-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Angadi Punnya Department of Oral and Maxillofacial Pathology and Microbiology, KLE VK Institute of Dental Sciences, Nehru Nagar, 590010, Belgaum, India aut NATIONALLICENCE 700 1- Rekha K. Department of Oral and Maxillofacial Pathology and Microbiology, SDM College of Dental Sciences, 580009, Dharwad, Karnataka, India aut NATIONALLICENCE 773 0- Oral and Maxillofacial Surgery Springer-Verlag 15/1(2011-03-01), 15-19 1865-1550 15:1<15 2011 15 10006 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer