caa a22 4500 445851163 CHVBK 20180317145414.0 cr unu---uuuuu 170323e20110901xx s 000 0 eng 10.1007/s10006-010-0239-4 doi (NATIONALLICENCE)springer-10.1007/s10006-010-0239-4 Eosinophilic ulcer: the role of stress-induced psychoneuroimmunologic factors [Elektronische Daten] [André Ribeiro, Fábio de Oliveira Mendes, Sérgio de Alves Jr, João de Pinheiro] Introduction: Eosinophilic ulcer (EU) is a rare pathology and its etiology is still slightly known. It is a benign lesion characterized by fast-growing ulceration with elevated and indurated borders, most commonly affecting the tongue. Case report: The authors describe a case of EU on a lingual border that was initiated and had its clinical behavior altered by the psychological stress the patient was experiencing. Discussion: This paper discusses the stress effects that alter the individual's immunologic response, thus attracting mast cells and eosinophils towards the mucosal epithelium, which are involved in eosinophilic ulcer. The authors make an association between eosinophilic ulcer and atopic dermatitis, two diseases that appear to have a similar, though not fully defined, etiology. The psychological stress factor was considered a predisponent factor for eosinophilic ulcer etiology and its interference in the etiology and evolution of this disease should be considered. Springer-Verlag, 2010 Eosinophilic ulcer nationallicence Oral pathology nationallicence Differential diagnosis nationallicence Squamous cell carcinoma nationallicence Ribeiro André Department of Oral and Maxillofacial Surgery, School of Dentistry, University Center of Pará-CESUPA, Belém, Brazil aut de Oliveira Mendes Fábio University Center of Pará-CESUPA, Belém, Brazil aut Alves Jr Sérgio de Department of Oral and Maxillofacial Pathology, School of Dentistry, University Center of Pará-CESUPA, Belém, Brazil aut Pinheiro João de Department of Oral and Maxillofacial Pathology, School of Dentistry, Federal University of Pará-UFPA, Belém, Brazil aut Oral and Maxillofacial Surgery Springer-Verlag 15/3(2011-09-01), 179-182 1865-1550 15:3<179 2011 15 10006 https://doi.org/10.1007/s10006-010-0239-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10006-010-0239-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ribeiro André Department of Oral and Maxillofacial Surgery, School of Dentistry, University Center of Pará-CESUPA, Belém, Brazil aut NATIONALLICENCE 700 1- de Oliveira Mendes Fábio University Center of Pará-CESUPA, Belém, Brazil aut NATIONALLICENCE 700 1- Alves Jr Sérgio de Department of Oral and Maxillofacial Pathology, School of Dentistry, University Center of Pará-CESUPA, Belém, Brazil aut NATIONALLICENCE 700 1- Pinheiro João de Department of Oral and Maxillofacial Pathology, School of Dentistry, Federal University of Pará-UFPA, Belém, Brazil aut NATIONALLICENCE 773 0- Oral and Maxillofacial Surgery Springer-Verlag 15/3(2011-09-01), 179-182 1865-1550 15:3<179 2011 15 10006 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer